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APLP2

Description amyloid beta precursor like protein 2
Image
GO Annotations Cellular Component
  • Nucleus
  • Endoplasmic Reticulum Lumen
  • Plasma Membrane
  • Membrane
  • Integral Component Of Membrane
  • Platelet Alpha Granule Membrane
  • Extracellular Exosome
Molecular Function
  • DNA Binding
  • Serine-type Endopeptidase Inhibitor Activity
  • Protein Binding
  • Heparin Binding
  • Identical Protein Binding
  • Transition Metal Ion Binding
Biological Process
  • Platelet Degranulation
  • G Protein-coupled Receptor Signaling Pathway
  • Negative Regulation Of Endopeptidase Activity
  • Post-translational Protein Modification
  • Cellular Protein Metabolic Process
Pathways
  • Platelet degranulation
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Post-translational protein phosphorylation
Drugs
  • Zinc
Diseases
GWAS
  • Blood protein levels ( 30072576)
Interacting Genes 22 interacting genes: AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 HGS HLA-A JUN JUNB KAT5 MAPK8 PIK3CA PRKCA PRNP RPL26 VKORC1 ZNF512B
Entrez ID 334
HPRD ID 00103
Ensembl ID ENSG00000084234
Uniprot IDs A0A140VJE9 B4E3I5 Q06481
PDB IDs 5JBT 5TPT
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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