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HRG
Description
histidine rich glycoprotein
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Plasma Membrane
Cell Surface
Platelet Alpha Granule Lumen
Endolysosome
Collagen-containing Extracellular Matrix
Extracellular Exosome
Blood Microparticle
Molecular Function
Endopeptidase Inhibitor Activity
Serine-type Endopeptidase Inhibitor Activity
Cysteine-type Endopeptidase Inhibitor Activity
Signaling Receptor Binding
Protein Binding
Heparin Binding
Zinc Ion Binding
Immunoglobulin Binding
Heme Binding
Heparan Sulfate Proteoglycan Binding
Metal Ion Binding
Biological Process
Angiogenesis
Platelet Degranulation
Positive Regulation Of Immune Response To Tumor Cell
Chemotaxis
Negative Regulation Of Cell Adhesion
Negative Regulation Of Cell Proliferation
Regulation Of Gene Expression
Regulation Of Platelet Activation
Negative Regulation Of Lamellipodium Assembly
Negative Regulation Of Endopeptidase Activity
Heme Transport
Negative Regulation Of Angiogenesis
Platelet Activation
Regulation Of Blood Coagulation
Negative Regulation Of Cell Growth
Regulation Of Actin Cytoskeleton Organization
Negative Regulation Of Cell Adhesion Mediated By Integrin
Fibrinolysis
Positive Regulation Of Apoptotic Process
Regulation Of Protein Complex Assembly
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Peptidyl-tyrosine Phosphorylation
Defense Response To Fungus
Cytolysis By Host Of Symbiont Cells
Positive Regulation Of Focal Adhesion Assembly
Negative Regulation Of Fibrinolysis
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Positive Regulation Of Blood Vessel Remodeling
Negative Regulation Of Endothelial Cell Chemotaxis
Pathways
Platelet degranulation
Dissolution of Fibrin Clot
Drugs
Diseases
Inherited thrombophilia
GWAS
Activated partial thromboplastin time (
22703881
20303064
)
Blood protein levels (
30072576
29875488
28240269
)
Neurological blood protein biomarker levels (
31320639
)
Interacting Genes
13 interacting genes:
C1QA
C1QB
CHRD
FCGR1A
FGA
FN1
PLG
PLSCR1
RABAC1
RCHY1
SPRY1
THBS1
TNFRSF1A
Entrez ID
3273
HPRD ID
00812
Ensembl ID
ENSG00000113905
Uniprot IDs
P04196
PDB IDs
Enriched GO Terms of Interacting Partners
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