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ACACB

Description acetyl-CoA carboxylase beta
Image
GO Annotations Cellular Component
  • Nucleus
  • Mitochondrion
  • Mitochondrial Outer Membrane
  • Cytosol
Molecular Function
  • Acetyl-CoA Carboxylase Activity
  • Protein Binding
  • ATP Binding
  • Biotin Binding
  • Identical Protein Binding
  • Metal Ion Binding
Biological Process
  • Acetyl-CoA Metabolic Process
  • Fatty Acid Biosynthetic Process
  • Carnitine Shuttle
  • Negative Regulation Of Gene Expression
  • Positive Regulation Of Lipid Storage
  • Regulation Of Glucose Metabolic Process
  • Response To Organic Cyclic Compound
  • Positive Regulation Of Cellular Metabolic Process
  • Response To Nutrient Levels
  • Negative Regulation Of Fatty Acid Beta-oxidation
  • Response To Drug
  • Negative Regulation Of Catalytic Activity
  • Regulation Of Cholesterol Biosynthetic Process
  • Protein Homotetramerization
  • Positive Regulation Of Heart Growth
  • Energy Homeostasis
  • Malonyl-CoA Biosynthetic Process
Pathways
  • ChREBP activates metabolic gene expression
  • Biotin transport and metabolism
  • Carnitine metabolism
  • Activation of gene expression by SREBF (SREBP)
Drugs
  • Biotin
  • Adenine
  • Soraphen A
  • 2-[4-(2,4-Dichlorophenoxy)Phenoxy]Propanoic Acid
  • (2S)-2-(4-{[3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]OXY}PHENOXY)PROPANOIC ACID
Diseases
GWAS
  • Triglycerides ( 30275531)
Interacting Genes 2 interacting genes: HLCS PRKAA2
Entrez ID 32
HPRD ID 07044
Ensembl ID ENSG00000076555
Uniprot IDs O00763
PDB IDs 2DN8 2HJW 2KCC 3FF6 3GID 3GLK 3JRW 3JRX 3TDC 4HQ6 5KKN
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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