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ACACA

Description acetyl-CoA carboxylase alpha
Image
GO Annotations Cellular Component
  • Fibrillar Center
  • Cytosol
  • Actin Cytoskeleton
Molecular Function
  • Acetyl-CoA Carboxylase Activity
  • Protein Binding
  • ATP Binding
  • Identical Protein Binding
  • Metal Ion Binding
Biological Process
  • Tissue Homeostasis
  • Acetyl-CoA Metabolic Process
  • Fatty Acid Biosynthetic Process
  • Carnitine Shuttle
  • Protein Metabolic Process
  • Positive Regulation Of Cellular Metabolic Process
  • Regulation Of Cholesterol Biosynthetic Process
  • Fatty-acyl-CoA Biosynthetic Process
  • Protein Homotetramerization
  • Lipid Homeostasis
  • Cellular Response To Prostaglandin E Stimulus
  • Malonyl-CoA Biosynthetic Process
Pathways
  • ChREBP activates metabolic gene expression
  • Biotin transport and metabolism
  • Carnitine metabolism
  • Activation of gene expression by SREBF (SREBP)
  • Defective HLCS causes multiple carboxylase deficiency
  • Fatty acyl-CoA biosynthesis
Drugs
  • Biotin
Diseases
GWAS
  • Ovarian cancer ( 23535730)
Interacting Genes 9 interacting genes: ATXN1 BRCA1 CHGB CSNK2A1 CSNK2A2 PRKAA1 PRKAA2 PRKAB1 PRKAG1
Entrez ID 31
HPRD ID 01938
Ensembl ID ENSG00000278540
Uniprot IDs A0A024R0Y2 Q13085 Q7Z5W8
PDB IDs 2YL2 3COJ 4ASI 6G2D 6G2H 6G2I
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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