HADH

Description		hydroxyacyl-CoA dehydrogenase
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	3-hydroxyacyl-CoA Dehydrogenase Activity NAD+ Binding
	Biological Process	Fatty Acid Beta-oxidation Response To Activity Response To Insulin Response To Drug Negative Regulation Of Insulin Secretion Positive Regulation Of Cold-induced Thermogenesis
Pathways		Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA Beta oxidation of hexanoyl-CoA to butanoyl-CoA Beta oxidation of butanoyl-CoA to acetyl-CoA
Drugs		NADH Acetoacetyl-CoA 3-Hydroxybutyryl-Coenzyme A
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757)
Interacting Genes		6 interacting genes: ADH1A APP CLK1 FBXO7 SLC2A4 STAT1
Entrez ID		3033
HPRD ID		08372
Ensembl ID		ENSG00000138796
Uniprot IDs		B3KTT6 Q16836
PDB IDs		1F0Y 1F12 1F14 1F17 1IL0 1LSJ 1LSO 1M75 1M76 2HDH 3HAD 3RQS
Enriched GO Terms of Interacting Partners?
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