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H1-1

Description H1.1 linker histone, cluster member
Image No pdb structure
GO Annotations Cellular Component
  • Nucleosome
  • Nuclear Chromatin
  • Nucleus
  • Nuclear Euchromatin
  • Cell Surface
  • Vesicle
Molecular Function
  • Double-stranded DNA Binding
  • Protein Binding
  • Heparin Binding
  • Chromatin DNA Binding
  • Nucleosomal DNA Binding
Biological Process
  • Nucleosome Assembly
  • Regulation Of Transcription, DNA-templated
  • Spermatogenesis
  • Nucleosome Positioning
  • Chromosome Condensation
  • Negative Regulation Of Chromatin Silencing
  • Negative Regulation Of DNA Recombination
  • Positive Regulation Of Receptor-mediated Endocytosis
Pathways
  • Apoptosis induced DNA fragmentation
  • Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
Interacting Genes 50 interacting genes: AEBP2 APP CCNA1 CCNA2 CCNB1 CCND2 CCNE1 CDK1 CDK2 CDK4 CDK5 CDK6 CDK7 CDKN1B CRP CTCFL EED EHMT2 EP300 EZH2 GADD45A GZMA IRAK4 KAT2B LIMK1 LIMK2 LOX NAP1L4 NASP NSD3 PAK4 PARP1 PARP3 PELP1 PRDM1 PRKCA PRKCB PRKCD PRKCE PRKCZ PRKDC PTMA RBBP4 RPS6KA5 SNCA SUZ12 TAF1 TERF1 TERF2IP TLK1
Entrez ID 3024
HPRD ID 00820
Ensembl ID ENSG00000124610
Uniprot IDs Q02539
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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