RGCC

Description		regulator of cell cycle
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Cytosol
	Molecular Function	Protein Binding Protein Kinase Binding Protein Kinase Activator Activity R-SMAD Binding
	Biological Process	Negative Regulation Of Exit From Mitosis Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Extracellular Matrix Constituent Secretion Complement Activation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Negative Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Angiogenesis Activation Of Protein Kinase Activity Positive Regulation Of Collagen Biosynthetic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cytokine Secretion Positive Regulation Of Cytokine Secretion Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Cell Cycle Arrest Cellular Response To Hypoxia Mitotic Cell Cycle Arrest Fibroblast Activation Negative Regulation Of Fibroblast Growth Factor Production Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of DNA Biosynthetic Process
Pathways		TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		3 interacting genes: AKT1 CDK1 PLK1
Entrez ID		28984
HPRD ID		17970
Ensembl ID		ENSG00000102760
Uniprot IDs		Q9H4X1
PDB IDs
Enriched GO Terms of Interacting Partners?
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