Wiki-CORONA
  • About
  • Search
  • Browse
  • Data Sources
  • People
  • Funding
  • Advanced Search

GNMT

Description glycine N-methyltransferase
Image
GO Annotations Cellular Component
  • Cytosol
Molecular Function
  • Protein Binding
  • Folic Acid Binding
  • Glycine Binding
  • Glycine N-methyltransferase Activity
  • Identical Protein Binding
  • S-adenosyl-L-methionine Binding
Biological Process
  • Glycogen Metabolic Process
  • Regulation Of Gluconeogenesis
  • Cellular Protein Modification Process
  • Methionine Metabolic Process
  • One-carbon Metabolic Process
  • Methylation
  • Cellular Nitrogen Compound Metabolic Process
  • S-adenosylhomocysteine Metabolic Process
  • S-adenosylmethionine Metabolic Process
  • Protein Homotetramerization
  • Sarcosine Metabolic Process
Pathways
  • Metabolism of ingested SeMet, Sec, MeSec into H2Se
  • Glyoxylate metabolism and glycine degradation
Drugs
  • Ademetionine
  • Glycine
  • S-adenosyl-L-homocysteine
  • Citric Acid
Diseases
  • Hypermethioninemia; Methionine adenosyltransferase deficiency; S-adenosylhomocysteine hydrolase deficiency
GWAS
  • Blood protein levels ( 30072576 29875488)
  • Plasma homocysteine levels (post-methionine load test) ( 24651765)
Interacting Genes 19 interacting genes: ADAMTSL4 ARR3 ARRB1 HDAC7 KRTAP10-3 KRTAP4-2 NIF3L1 NOTCH2NLA NTAQ1 NUDT18 PLEKHF2 POT1 PRKACA RPSA SDCBP TERF1 TERF2 TERF2IP TINF2
Entrez ID 27232
HPRD ID 05970
Ensembl ID ENSG00000124713
Uniprot IDs A0A0S2Z5F2 Q14749 V9HW60
PDB IDs 1R74 2AZT
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

  • Tweet