FGF22

Description		fibroblast growth factor 22
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleolus Golgi Apparatus Cell Surface
	Molecular Function	Fibroblast Growth Factor Receptor Binding Growth Factor Activity
	Biological Process	MAPK Cascade Fibroblast Growth Factor Receptor Signaling Pathway Cell Differentiation Positive Regulation Of Protein Kinase B Signaling
Pathways		PI3K Cascade PIP3 activates AKT signaling FGFR1b ligand binding and activation FGFR2b ligand binding and activation Activated point mutants of FGFR2 Constitutive Signaling by Aberrant PI3K in Cancer Phospholipase C-mediated cascade: FGFR1 Phospholipase C-mediated cascade; FGFR2 Downstream signaling of activated FGFR1 SHC-mediated cascade:FGFR1 PI-3K cascade:FGFR1 FRS-mediated FGFR1 signaling PI-3K cascade:FGFR2 SHC-mediated cascade:FGFR2 FRS-mediated FGFR2 signaling Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Signaling by FGFR2 in disease FGFRL1 modulation of FGFR1 signaling RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS
Interacting Genes		1 interacting genes: PTX3
Entrez ID		27006
HPRD ID		05784
Ensembl ID		ENSG00000070388
Uniprot IDs		K7ELB9 Q9HCT0
PDB IDs
Enriched GO Terms of Interacting Partners?
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