ALOX12B

Description		arachidonate 12-lipoxygenase, 12R type
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Arachidonate 12-lipoxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen Lyase Activity Isomerase Activity Arachidonate 8(R)-lipoxygenase Activity Linoleate 9S-lipoxygenase Activity
	Biological Process	Protein Lipidation Sphingolipid Metabolic Process Positive Regulation Of Gene Expression Arachidonic Acid Metabolic Process Lipoxygenase Pathway Lipid Oxidation Positive Regulation Of MAPK Cascade Linoleic Acid Metabolic Process Ceramide Biosynthetic Process Hepoxilin Biosynthetic Process Oxidation-reduction Process Establishment Of Skin Barrier Positive Regulation Of Mucus Secretion
Pathways		Synthesis of 12-eicosatetraenoic acid derivatives
Drugs
Diseases		Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS
Interacting Genes		2 interacting genes: KRT5 LMNA
Entrez ID		242
HPRD ID		04772
Ensembl ID		ENSG00000179477
Uniprot IDs		O75342
PDB IDs
Enriched GO Terms of Interacting Partners?
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