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PADI4

Description peptidyl arginine deiminase 4
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • Protein-containing Complex
Molecular Function
  • Protein-arginine Deiminase Activity
  • Calcium Ion Binding
  • Protein Binding
  • Arginine Binding
  • Identical Protein Binding
Biological Process
  • Chromatin Organization
  • Nucleosome Assembly
  • Chromatin Remodeling
  • Cellular Protein Modification Process
  • Protein Citrullination
  • Stem Cell Population Maintenance
  • Histone H3-R26 Citrullination
  • Histone Citrullination
  • Innate Immune Response
Pathways
  • Chromatin modifying enzymes
Drugs
  • L-Citrulline
  • Azithromycin
  • Doxycycline
  • Tetracycline
  • Streptomycin
  • N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE
Diseases
GWAS
  • Basal cell carcinoma ( 18849993)
  • IgA nephropathy ( 25305756)
  • Rheumatoid arthritis ( 21452313 21505073 30423114 23143596 24390342)
  • Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
Interacting Genes 8 interacting genes: ANXA4 APP FBXO25 H3C15 HDAC2 LRRK2 NPM1 SMURF1
Entrez ID 23569
HPRD ID 05635
Ensembl ID ENSG00000159339
Uniprot IDs Q9UM07
PDB IDs 1WD8 1WD9 1WDA 2DEW 2DEX 2DEY 2DW5 3APM 3APN 3B1T 3B1U 4DKT 4X8C 4X8G 5N0M 5N0Y 5N0Z 5N1B
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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