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FOSB

Description FosB proto-oncogene, AP-1 transcription factor subunit
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GO Annotations Cellular Component
  • Nuclear Chromatin
  • Nucleus
  • Nucleoplasm
  • Intracellular Membrane-bounded Organelle
Molecular Function
  • RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
  • DNA Binding
  • Protein Binding
  • Transcription Factor Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Regulation Of Transcription By RNA Polymerase II
  • Transcription By RNA Polymerase II
  • Female Pregnancy
  • Response To Mechanical Stimulus
  • Response To Progesterone
  • Cellular Response To Hormone Stimulus
  • Response To Morphine
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Response To Corticosterone
  • Response To CAMP
  • Cellular Response To Calcium Ion
Pathways
  • Estrogen-dependent gene expression
  • NGF-stimulated transcription
Drugs
Diseases
GWAS
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Heel bone mineral density ( 30598549 28869591)
Interacting Genes 6 interacting genes: DNMT3L EP300 JUN JUNB JUND SRA1
Entrez ID 2354
HPRD ID 01270
Ensembl ID ENSG00000125740
Uniprot IDs A0A024R0P6 K7EKC1 P53539
PDB IDs 5VPA 5VPB 5VPC 5VPD 5VPE 5VPF
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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