TNFRSF13B

Description		TNF receptor superfamily member 13B
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Signaling Receptor Activity
	Biological Process	B Cell Homeostasis Hematopoietic Progenitor Cell Differentiation Adaptive Immune Response Cell Surface Receptor Signaling Pathway Negative Regulation Of B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway
Pathways		TNFs bind their physiological receptors
Drugs
Diseases		Common variable immunodeficiency (CVID), including the following four diseases: Inducible T Cell costimulator (ICOS) defect; TACI defect; CD19 defect; BAFFR defect
GWAS		Albumin-globulin ratio ( 29403010) Diabetic retinopathy ( 21441570) Granulocyte percentage of myeloid white cells ( 27863252) Hematological and biochemical traits ( 20139978) Hematology traits ( 23303382) IgG levels ( 22673310) Immunoglobulin light chain (AL) amyloidosis ( 28025584) Immunoglobulin measurement (zinc sulfate turbidity test) ( 29403010) Lymphocyte counts ( 27863252) Monoclonal gammopathy of undetermined significance ( 30737484) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Multiple myeloma ( 26007630 23955597) Multiple myeloma and monoclonal gammopathy ( 26007630) Non-albumin protein levels ( 22558069 29403010) Platelet count ( 27863252) Plateletcrit ( 27863252) Serum albumin level ( 29403010) Serum total protein level ( 23022100 29403010) Sodium levels ( 29403010) Tonsillectomy ( 27182965 28928442)
Interacting Genes		7 interacting genes: CAMLG SGTA TNFSF13 TNFSF13B TRAF2 TRAF5 TRAF6
Entrez ID		23495
HPRD ID		05365
Ensembl ID		ENSG00000240505
Uniprot IDs		O14836 Q4ACX1
PDB IDs		1XU1 1XUT
Enriched GO Terms of Interacting Partners?
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