KDM4C

Description		lysine demethylase 4C
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Pericentric Heterochromatin Histone Methyltransferase Complex
	Molecular Function	Chromatin Binding Zinc Ion Binding Enzyme Binding Histone Demethylase Activity Histone Demethylase Activity (H3-K9 Specific) Androgen Receptor Binding Histone Demethylase Activity (H3-K36 Specific)
	Biological Process	Blastocyst Formation Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Stem Cell Population Maintenance Histone H3-K9 Demethylation Positive Regulation Of Neuron Differentiation Oxidation-reduction Process Histone H3-K36 Demethylation Negative Regulation Of Histone H3-K9 Trimethylation Regulation Of Stem Cell Differentiation
Pathways		HDMs demethylate histones Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Drugs
Diseases
GWAS		Alanine transaminase levels ( 29403010) Artificially sweetened beverage consumption ( 31046077) Body mass index ( 25673413) California verbal learning test score ( 31596458) HIV-1 susceptibility ( 25786224) Menarche (age at onset) ( 25231870) Radiation response ( 20923822) Response to fenofibrate (adiponectin levels) ( 23149075) Schizophrenia ( 30285260) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Systemic lupus erythematosus ( 26606652)
Interacting Genes		2 interacting genes: H3C1 H3C14
Entrez ID		23081
HPRD ID		12016
Ensembl ID		ENSG00000107077
Uniprot IDs		B0QZ60 Q9H3R0
PDB IDs		2XDP 2XML 4XDO 4XDP 5FJH 5FJK 5KR7
Enriched GO Terms of Interacting Partners?
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