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NINL

Description ninein like
Image No pdb structure
GO Annotations Cellular Component
  • Centrosome
  • Cytosol
  • Microtubule
  • Intercellular Bridge
Molecular Function
  • Calcium Ion Binding
  • Protein Binding
Biological Process
  • G2/M Transition Of Mitotic Cell Cycle
  • Regulation Of G2/M Transition Of Mitotic Cell Cycle
  • Microtubule Anchoring At Centrosome
  • Ciliary Basal Body-plasma Membrane Docking
Pathways
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
Drugs
Diseases
GWAS
  • Macular thickness ( 30535121)
  • Telomere length ( 30185882)
  • Urate levels ( 31578528)
Interacting Genes 50 interacting genes: AKAP17A APEX2 APMAP AURKB CBY2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 ELOA EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 KRT1 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 POLR3F RBM41 RCOR3 RGS2 RIBC2 SEC23B SH2D4A SH3BP5L SYT17 TCEANC TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646
Entrez ID 22981
HPRD ID 11120
Ensembl ID ENSG00000101004
Uniprot IDs Q9Y2I6
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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