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MAPRE1
Description
microtubule associated protein RP/EB family member 1
Image
GO Annotations
Cellular Component
Golgi Apparatus
Centrosome
Microtubule Organizing Center
Spindle
Cytosol
Microtubule
Cytoplasmic Microtubule
Focal Adhesion
Cortical Microtubule Cytoskeleton
Cell Projection Membrane
Microtubule Plus-end
Spindle Midzone
Mitotic Spindle Astral Microtubule End
Molecular Function
RNA Binding
Protein Binding
Microtubule Binding
Protein C-terminus Binding
Protein Kinase Binding
Identical Protein Binding
Cadherin Binding
Microtubule Plus-end Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Microtubule Bundle Formation
Protein Localization
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cell Migration
Positive Regulation Of Cell Migration
Regulation Of Microtubule Polymerization Or Depolymerization
Negative Regulation Of Microtubule Polymerization
Positive Regulation Of Microtubule Polymerization
Protein Localization To Microtubule
Microtubule Polymerization
Spindle Assembly
Cell Division
Ciliary Basal Body-plasma Membrane Docking
Positive Regulation Of Microtubule Plus-end Binding
Protein Localization To Microtubule Plus-end
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Iron status biomarkers (transferrin saturation) (
28334935
)
Polycystic ovary syndrome (
30566500
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Interacting Genes
44 interacting genes:
ABCB1
APC
APC2
APP
AURKB
BCL3
CASK
CDK5RAP2
CLASP1
CLASP2
COPS5
COPS8
CSN3
CYLD
DCTN1
GTSE1
HSPA1A
IKBKG
KAT2B
KAT5
KLHL21
LMO2
LRP1
MACF1
MAPRE2
MAPRE3
NAV1
NUPR1
PIK3R4
POLE2
PQBP1
PRPF3
PSMA1
SLAIN1
SPDYE2
SRC
SRPK2
STK11
TERF1
TRAF2
TRIO
TROAP
TUBA1A
TUBB
Entrez ID
22919
HPRD ID
04379
Ensembl ID
ENSG00000101367
Uniprot IDs
Q15691
PDB IDs
1PA7
1TXQ
1UEG
1VKA
1WU9
1YIB
1YIG
2HKQ
2HL3
2HL5
2QJZ
2R8U
3GJO
3MTU
3MUD
3TQ7
4XA1
4XA3
4XA6
5JV3
5JVM
5JVP
5JVR
5JVS
5JVU
5JX1
5WLQ
Enriched GO Terms of Interacting Partners
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