FGF3

Description		fibroblast growth factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	MAPK Cascade Signal Transduction Cell-cell Signaling Multicellular Organism Development Positive Regulation Of Cell Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Cell Division Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Cardiac Muscle Tissue Development
Pathways		PI3K Cascade PIP3 activates AKT signaling FGFR1b ligand binding and activation FGFR2b ligand binding and activation Activated point mutants of FGFR2 Constitutive Signaling by Aberrant PI3K in Cancer Phospholipase C-mediated cascade: FGFR1 Phospholipase C-mediated cascade; FGFR2 Downstream signaling of activated FGFR1 SHC-mediated cascade:FGFR1 PI-3K cascade:FGFR1 FRS-mediated FGFR1 signaling PI-3K cascade:FGFR2 SHC-mediated cascade:FGFR2 FRS-mediated FGFR2 signaling Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Signaling by FGFR2 in disease FGFRL1 modulation of FGFR1 signaling RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases		Kaposi's sarcoma
GWAS		Attention deficit hyperactivity disorder ( 29325848) Breast cancer ( 20453838) Childhood ear infection ( 27182965 28928442) Craniofacial microsomia ( 26853712) Lean body mass ( 28552196) Monobrow ( 27182965) Protein quantitative trait loci ( 18464913) Urate levels in overweight individuals ( 25811787) White blood cell count (basophil) ( 29403010)
Interacting Genes		6 interacting genes: EBNA1BP2 FGFR1 FGFR2 FGFR3 FGFR4 RPS2
Entrez ID		2248
HPRD ID		01289
Ensembl ID		ENSG00000186895
Uniprot IDs		P11487
PDB IDs
Enriched GO Terms of Interacting Partners?
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