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GPC4

Description glypican 4
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Nucleus
  • Golgi Lumen
  • Plasma Membrane
  • External Side Of Plasma Membrane
  • Cell Surface
  • Lysosomal Lumen
  • Synapse
  • Collagen-containing Extracellular Matrix
  • Extracellular Exosome
  • Glutamatergic Synapse
  • Anchored Component Of Presynaptic Membrane
Molecular Function
  • Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
Biological Process
  • Retinoid Metabolic Process
  • Glycosaminoglycan Biosynthetic Process
  • Glycosaminoglycan Catabolic Process
  • Regulation Of Signal Transduction
  • Cell Migration
  • Wnt Signaling Pathway, Planar Cell Polarity Pathway
  • Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane
  • Synaptic Membrane Adhesion
  • Regulation Of Protein Localization To Membrane
  • Regulation Of Presynapse Assembly
Pathways
  • A tetrasaccharide linker sequence is required for GAG synthesis
  • HS-GAG biosynthesis
  • HS-GAG biosynthesis
  • HS-GAG degradation
  • Defective B4GALT7 causes EDS, progeroid type
  • Defective B3GAT3 causes JDSSDHD
  • Defective EXT2 causes exostoses 2
  • Defective EXT1 causes exostoses 1, TRPS2 and CHDS
  • Defective B3GALT6 causes EDSP2 and SEMDJL1
  • Retinoid metabolism and transport
Drugs
Diseases
GWAS
Interacting Genes 9 interacting genes: ABHD17A ACP5 AKAP9 CCNC COL18A1 FGF2 PTEN PTPRD PTPRF
Entrez ID 2239
HPRD ID 02160
Ensembl ID ENSG00000076716
Uniprot IDs O75487
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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