FGD2

Description		FYVE, RhoGEF and PH domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Lamellipodium Early Endosome Membrane Ruffle Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Cytoskeleton Organization G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Apoptotic Process Regulation Of GTPase Activity Positive Regulation Of JUN Kinase Activity Filopodium Assembly Regulation Of Small GTPase Mediated Signal Transduction
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Medication use (thyroid preparations) ( 31015401) Rosacea symptom severity ( 29771307)
Interacting Genes		2 interacting genes: KLHL12 TMEM239
Entrez ID		221472
HPRD ID		05478
Ensembl ID		ENSG00000146192
Uniprot IDs		Q7Z6J4
PDB IDs
Enriched GO Terms of Interacting Partners?
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