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FANCD2

Description FA complementation group D2
Image No pdb structure
GO Annotations Cellular Component
  • Condensed Chromosome
  • Nucleus
  • Nucleoplasm
  • Nucleolus
  • Cytosol
  • Nuclear Body
Molecular Function
  • Protein Binding
  • DNA Polymerase Binding
Biological Process
  • Synapsis
  • Gamete Generation
  • Response To Gamma Radiation
  • Intra-S DNA Damage Checkpoint
  • Cellular Response To Oxidative Stress
  • Interstrand Cross-link Repair
  • Regulation Of Regulatory T Cell Differentiation
  • Brain Morphogenesis
  • Regulation Of Inflammatory Response
  • Regulation Of DNA-binding Transcription Factor Activity
  • Neuronal Stem Cell Population Maintenance
  • Double-strand Break Repair Involved In Meiotic Recombination
  • Regulation Of CD40 Signaling Pathway
Pathways
  • Fanconi Anemia Pathway
  • TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases
  • Fanconi anemia
GWAS
  • Alzheimer's disease ( 24755620)
  • Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes 28 interacting genes: ATM ATR BLM BRCA1 BRCA2 BRIP1 FANCC FANCE FANCI FANCL H2AC4 H2BC3 H3C1 H4C1 MEN1 MRE11 NBN PCNA RAD51 TERF1 TNFRSF1A TNFRSF1B TNKS UBB UBE2T UHRF1 UHRF2 USP1
Entrez ID 2177
HPRD ID 01968
Ensembl ID ENSG00000144554
Uniprot IDs Q9BXW9
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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