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ABCA2
Description
ATP binding cassette subfamily A member 2
Image
No pdb structure
GO Annotations
Cellular Component
Cell
Lysosome
Lysosomal Membrane
Endosome
Microtubule Organizing Center
Plasma Membrane
Endosome Membrane
Membrane
Integral Component Of Membrane
Cytoplasmic Vesicle
ATP-binding Cassette (ABC) Transporter Complex
Intracellular Membrane-bounded Organelle
Molecular Function
Nucleotide Binding
Lipid Transporter Activity
ATP Binding
ATPase Activity
ATPase Activity, Coupled To Transmembrane Movement Of Substances
Endopeptidase Regulator Activity
Ceramide-translocating ATPase Activity
Biological Process
Regulation Of Transcription By RNA Polymerase II
Lipid Metabolic Process
Lipid Transport
Locomotory Behavior
Regulation Of Cholesterol Esterification
Central Nervous System Myelin Formation
Regulation Of Intracellular Cholesterol Transport
Negative Regulation Of Intracellular Cholesterol Transport
Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process
Response To Drug
Cholesterol Homeostasis
Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process
Regulation Of Cholesterol Biosynthetic Process
Sphingosine Biosynthetic Process
Response To Steroid Hormone
Regulation Of Endopeptidase Activity
Transmembrane Transport
Regulation Of Protein Glycosylation
Response To Cholesterol
Negative Regulation Of Phospholipid Biosynthetic Process
Negative Regulation Of Sphingolipid Biosynthetic Process
Cellular Sphingolipid Homeostasis
Negative Regulation Of Cholesterol Efflux
Ceramide Translocation
Regulation Of Post-translational Protein Modification
Positive Regulation Of Amyloid-beta Formation
Positive Regulation Of Amyloid Precursor Protein Catabolic Process
Regulation Of Protein Localization To Cell Periphery
Negative Regulation Of Low-density Lipoprotein Receptor Activity
Negative Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport
Regulation Of Protein Localization To Cell Surface
Pathways
ABC transporters in lipid homeostasis
Drugs
Diseases
GWAS
Adverse response to drug (
30420678
)
Interacting Genes
2 interacting genes:
CACNA1A
CDK5RAP2
Entrez ID
20
HPRD ID
08967
Ensembl ID
ENSG00000107331
Uniprot IDs
Q9BZC7
PDB IDs
Enriched GO Terms of Interacting Partners
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