AGO4

Description		argonaute RISC component 4
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GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Membrane RISC Complex RISC-loading Complex
	Molecular Function	Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding MiRNA Binding
	Biological Process	MRNA Catabolic Process Synaptonemal Complex Assembly Male Meiotic Nuclear Division Wnt Signaling Pathway, Calcium Modulating Pathway Male Gonad Development RNA Secondary Structure Unwinding MiRNA Metabolic Process Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Cell Morphogenesis Pre-miRNA Processing Posttranscriptional Gene Silencing By RNA Production Of MiRNAs Involved In Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation MRNA Cleavage Involved In Gene Silencing By MiRNA MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Negative Regulation Of Apoptotic Process Regulation Of Megakaryocyte Differentiation MRNA Cleavage Involved In Gene Silencing By SiRNA
Pathways		Pre-NOTCH Transcription and Translation MicroRNA (miRNA) biogenesis Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway Small interfering RNA (siRNA) biogenesis Post-transcriptional silencing by small RNAs TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: APP G3BP2 TNRC6A TNRC6B TNRC6C
Entrez ID		192670
HPRD ID		09559
Ensembl ID		ENSG00000134698
Uniprot IDs		Q9HCK5
PDB IDs		6OON
Enriched GO Terms of Interacting Partners?
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