DDX1

Description		DEAD-box helicase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Cytoplasmic Stress Granule Membrane Cleavage Body TRNA-splicing Ligase Complex Ribonucleoprotein Complex
	Molecular Function	DNA Binding Chromatin Binding Transcription Coregulator Activity RNA Binding RNA Helicase Activity Double-stranded RNA Binding Helicase Activity Nuclease Activity Exonuclease Activity Protein Binding ATP Binding Poly(A) Binding DNA/RNA Helicase Activity
	Biological Process	Spliceosomal Complex Assembly Positive Regulation Of Myeloid Dendritic Cell Cytokine Production Double-strand Break Repair TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Regulation Of Translational Initiation Multicellular Organism Development Viral Process DNA Duplex Unwinding Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Innate Immune Response Defense Response To Virus Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Nucleic Acid-templated Transcription Protein Localization To Cytoplasmic Stress Granule
Pathways		tRNA processing in the nucleus
Drugs
Diseases
GWAS		Asthma or chronic obstructive pulmonary disease ( 24993907) Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 22479191) Chronic obstructive pulmonary disease ( 30804561) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Metabolite levels ( 23823483) Pulmonary function ( 21946350) Pulmonary function (smoking interaction) ( 23284291) Urate levels ( 31578528) Wilms tumor ( 22544364)
Interacting Genes		9 interacting genes: APP ATM CSTF2 ESR1 HNRNPK NDRG1 NME7 RELA YWHAQ
Entrez ID		1653
HPRD ID		03158
Ensembl ID		ENSG00000079785
Uniprot IDs		A3RJH1 Q92499
PDB IDs		4XW3
Enriched GO Terms of Interacting Partners?
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