CTRB1

Description		chymotrypsinogen B1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Serine-type Endopeptidase Activity
	Biological Process	Proteolysis Digestion Cobalamin Metabolic Process Extracellular Matrix Disassembly
Pathways		Activation of Matrix Metalloproteinases Cobalamin (Cbl, vitamin B12) transport and metabolism
Drugs		Trans-O-Hydroxy-Alpha-Methyl Cinnamate 2,4-Dihydroxy-Trans Cinnamic Acid Phenylethane Boronic Acid Phosphorylisopropane Aprotinin 1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE 3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID 2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE (2S) N-acetyl-L-alanyl-Î±L-phenylalanyl-chloroethylketone 1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) (3S)-3-Amino-1-chloro-4-phenyl-2-butanone L-1-naphthyl-2-acetamido-ethane boronic acid D-1-naphthyl-2-acetamido-ethane boronic acid D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143) Pancreatic cancer ( 25086665) Type 2 diabetes ( 30054458)
Interacting Genes		4 interacting genes: LYPD3 SERPINA1 SERPINA3 SERPINF2
Entrez ID		1504
HPRD ID		00345
Ensembl ID		ENSG00000168925
Uniprot IDs		P17538
PDB IDs
Enriched GO Terms of Interacting Partners?
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