DIS3L2

Description		DIS3 like 3'-5' exoribonuclease 2
Image		No pdb structure
GO Annotations	Cellular Component	Exosome (RNase Complex) P-body Cytoplasm Polysome
	Molecular Function	3'-5'-exoribonuclease Activity Magnesium Ion Binding Ribonuclease Activity Protein Binding Poly(U) RNA Binding
	Biological Process	Mitotic Cell Cycle Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic MRNA Catabolic Process Negative Regulation Of Cell Proliferation MiRNA Catabolic Process Stem Cell Population Maintenance Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' Cell Division Mitotic Sister Chromatid Separation RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Polyuridylation-dependent MRNA Catabolic Process
Pathways
Drugs
Diseases
GWAS		Chronic back pain ( 30261039) Height ( 28552196 25282103 25429064 23563607 31562340 19570815 18391951 20189936) Hip circumference adjusted for BMI ( 25673412) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes		3 interacting genes: COPS6 FEZ1 VIM
Entrez ID		129563
HPRD ID		14619
Ensembl ID		ENSG00000144535
Uniprot IDs		Q8IYB7
PDB IDs
Enriched GO Terms of Interacting Partners?
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