PIK3AP1

Description		phosphoinositide-3-kinase adaptor protein 1
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GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Inflammatory Response Positive Regulation Of Protein Kinase B Signaling
Pathways		PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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Diseases
GWAS		Alanine transaminase levels ( 29403010) Monocyte percentage of white cells ( 27863252) Orthostatic hypotension ( 24124408)
Interacting Genes		7 interacting genes: BTK GRB2 ITSN1 ITSN2 NCK2 PIK3R1 SYK
Entrez ID		118788
HPRD ID		06401
Ensembl ID		ENSG00000155629
Uniprot IDs		Q6ZUJ8 Q86YV3
PDB IDs		5FOR
Enriched GO Terms of Interacting Partners?
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