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PADI2

Description peptidyl arginine deiminase 2
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Transcriptionally Active Chromatin
  • Azurophil Granule Lumen
  • Extracellular Exosome
Molecular Function
  • Protein-arginine Deiminase Activity
  • Calcium Ion Binding
  • Estrogen Receptor Binding
  • Protein Homodimerization Activity
Biological Process
  • Chromatin Organization
  • Regulation Of Chromatin Disassembly
  • Protein Citrullination
  • Substantia Nigra Development
  • Intracellular Estrogen Receptor Signaling Pathway
  • Histone H3-R26 Citrullination
  • Histone Citrullination
  • Neutrophil Degranulation
  • Chromatin-mediated Maintenance Of Transcription
  • Negative Regulation Of Chemokine-mediated Signaling Pathway
  • Negative Regulation Of Lymphocyte Chemotaxis
  • Cellular Response To Leukemia Inhibitory Factor
Pathways
  • Chromatin modifying enzymes
  • Neutrophil degranulation
Drugs
  • L-Citrulline
Diseases
GWAS
  • Prudent dietary pattern ( 28644415)
  • Rheumatoid arthritis ( 30423114)
  • Visceral fat ( 30942860)
Interacting Genes 1 interacting genes: EMC1
Entrez ID 11240
HPRD ID 06396
Ensembl ID ENSG00000117115
Uniprot IDs Q9Y2J8
PDB IDs 4N20 4N22 4N24 4N25 4N26 4N28 4N2A 4N2B 4N2C 4N2D 4N2E 4N2F 4N2G 4N2H 4N2I 4N2K 4N2L 4N2M 4N2N
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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