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DBF4

Description DBF4 zinc finger
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Nuclear Body
  • Dbf4-dependent Protein Kinase Complex
Molecular Function
  • Nucleic Acid Binding
  • Protein Binding
  • Enzyme Activator Activity
  • Zinc Ion Binding
  • Protein Serine/threonine Kinase Activator Activity
Biological Process
  • G1/S Transition Of Mitotic Cell Cycle
  • DNA Replication
  • Positive Regulation Of Nuclear Cell Cycle DNA Replication
  • Positive Regulation Of Protein Serine/threonine Kinase Activity
  • Regulation Of Cell Cycle Phase Transition
Pathways
  • Activation of ATR in response to replication stress
  • Activation of the pre-replicative complex
Drugs
Diseases
GWAS
  • Metabolite levels ( 23823483)
Interacting Genes 18 interacting genes: BRCA1 CDC7 CDK2 CHAF1A CHEK2 LSM8 MCM2 MCM3 MCM4 MCM6 MCM7 MCMBP MEN1 ORC1 ORC2 ORC3 ORC5 ORC6
Entrez ID 10926
HPRD ID 10371
Ensembl ID ENSG00000006634
Uniprot IDs B4DXK0 B7Z8C6 Q9UBU7
PDB IDs 4F99 4F9A 4F9B 4F9C
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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