MASP2

Description		mannan binding lectin serine peptidase 2
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Exosome
	Molecular Function	Complement Component C4b Binding Serine-type Endopeptidase Activity Calcium Ion Binding Protein Binding Peptidase Activity Calcium-dependent Protein Binding
	Biological Process	Complement Activation, Lectin Pathway Proteolysis Complement Activation Complement Activation, Classical Pathway
Pathways
Drugs		Beta-Hydroxyasparagine
Diseases		Mannose-binding lectin pathway component defects, including the following two diseases: Mannose-binding lectin deficiency; Mannose-binding lectin-associated serine protease (MASP) 2 deficiency
GWAS		Beard thickness ( 26926045) Body mass index ( 29273807) Male-pattern baldness ( 28196072)
Interacting Genes		3 interacting genes: FCN2 MBL2 SERPING1
Entrez ID		10747
HPRD ID		05484
Ensembl ID		ENSG00000009724
Uniprot IDs		O00187
PDB IDs		1Q3X 1SZB 1ZJK 3TVJ 4FXG 5JPM
Enriched GO Terms of Interacting Partners?
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