CES1

Description		carboxylesterase 1
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GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol
	Molecular Function	Sterol Esterase Activity Triglyceride Lipase Activity Methylumbelliferyl-acetate Deacetylase Activity Carboxylic Ester Hydrolase Activity Methyl Indole-3-acetate Esterase Activity
	Biological Process	Angiotensin Maturation Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Response To Toxic Substance Lipid Catabolic Process Epithelial Cell Differentiation Medium-chain Fatty Acid Metabolic Process Cholesterol Ester Hydrolysis Involved In Cholesterol Transport
Pathways		Metabolism of Angiotensinogen to Angiotensins Phase I - Functionalization of compounds
Drugs		Oseltamivir Tacrine Pethidine L-Carnitine Dextropropoxyphene Cocaine Naloxone Heroin Probucol Hydroxy-Phenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester Cholic Acid 4-Piperidino-Piperidine N-acetyl-alpha-neuraminic acid N-Methylnaloxonium Thenoyltrifluoroacetone Cyclandelate (1R)-1,2,2-trimethylpropyl (R)-methylphosphinate (1S,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-7-METHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HY DROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENOL Homatropine
Diseases
GWAS		Response to dabigatran etexilate treatment ( 23467860)
Interacting Genes		3 interacting genes: BMPR2 CREB3 GUSB
Entrez ID		1066
HPRD ID		00268
Ensembl ID		ENSG00000198848
Uniprot IDs		P23141
PDB IDs		1MX1 1MX5 1MX9 1YA4 1YA8 1YAH 1YAJ 2DQY 2DQZ 2DR0 2H7C 2HRQ 2HRR 3K9B 4AB1 5A7F 5A7G 5A7H
Enriched GO Terms of Interacting Partners?
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