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HEXIM1

Description HEXIM P-TEFb complex subunit 1
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Intracellular Membrane-bounded Organelle
Molecular Function
  • Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
  • Protein Binding
  • SnRNA Binding
  • Identical Protein Binding
  • 7SK SnRNA Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Activation Of Innate Immune Response
  • Heart Development
  • Innate Immune Response
  • Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
  • Negative Regulation Of Transcription, DNA-templated
  • Positive Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 31619474)
  • Craniofacial microsomia ( 26853712)
  • Male-pattern baldness ( 28196072)
  • Systolic blood pressure ( 19430483)
Interacting Genes 10 interacting genes: CCNT1 CCNT2 CDK9 EGFR ESR1 RELA RN7SK TERF1 TERF2 UBE2O
Entrez ID 10614
HPRD ID 09544
Ensembl ID ENSG00000186834
Uniprot IDs O94992
PDB IDs 2GD7 3S9G
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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