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CENPC

Description centromere protein C
Image
GO Annotations Cellular Component
  • Kinetochore
  • Condensed Nuclear Chromosome Kinetochore
  • Condensed Nuclear Chromosome, Centromeric Region
  • Cell
  • Nucleoplasm
  • Pericentric Heterochromatin
  • Cytosol
  • Nuclear Body
  • Midbody
  • Nuclear Pericentric Heterochromatin
Molecular Function
  • DNA Binding
  • Protein Binding
  • Centromeric DNA Binding
  • Identical Protein Binding
Biological Process
  • Mitotic Cell Cycle
  • Chromosome Segregation
  • CENP-A Containing Nucleosome Assembly
  • Cell Division
  • Attachment Of Mitotic Spindle Microtubules To Kinetochore
  • Kinetochore Assembly
  • Attachment Of Spindle Microtubules To Kinetochore Involved In Homologous Chromosome Segregation
Pathways
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
  • Adverse response to drug ( 30420678)
  • Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)
Interacting Genes 7 interacting genes: DAXX ELOC MAPK14 MDC1 SUMO2 TRIM14 UBTF
Entrez ID 1060
HPRD ID 00315
Ensembl ID ENSG00000145241
Uniprot IDs Q03188
PDB IDs 5LSJ 5LSK 6MUO 6MUP 6SE6 6SEE 6SEF
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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