UBAP2L and PLXNA2

Number of citations: 39 (PubMedID 12421765)
Data Source: HPRD (two hybrid)

		UBAP2L	PLXNA2
Name		ubiquitin associated protein 2 like	plexin A2
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Cytoplasm Cytoplasmic Stress Granule PcG Protein Complex	Semaphorin Receptor Complex Plasma Membrane Membrane
	Molecular Function	RNA Binding Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Semaphorin Receptor Activity Identical Protein Binding
	Biological Process	Binding Of Sperm To Zona Pellucida Stress Granule Assembly Hematopoietic Stem Cell Homeostasis Positive Regulation Of Stress Granule Assembly	Somitogenesis Cell Surface Receptor Signaling Pathway Nervous System Development Synapse Assembly Anatomical Structure Morphogenesis Neural Tube Development Cerebellar Granule Cell Precursor Tangential Migration Regulation Of Cell Migration Tube Development Animal Organ Development Centrosome Localization Pharyngeal System Development Limb Bud Formation Semaphorin-plexin Signaling Pathway
Pathways		None	Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling Other semaphorin interactions
GWAS		Bipolar disorder ( 31043756 ) Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Cortical surface area (min-P) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) Cortical thickness (min-P) ( 32665545 ) Cortical thickness (MOSTest) ( 32665545 ) Diastolic blood pressure ( 30224653 ) Fish- and plant-related diet ( 32066663 ) Smoking initiation ( 30617275 33082346 ) Subcortical volume (min-P) ( 32665545 ) Subcortical volume (MOSTest) ( 32665545 )	Adolescent idiopathic scoliosis ( 31417091 ) Bitter alcoholic beverage consumption ( 31046077 ) Cardiac hypertrophy ( 21348951 ) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189 ) General risk tolerance (MTAG) ( 30643258 ) Lung cancer in never smokers ( 28604730 ) Manganese levels ( 26025379 ) Pursuit maintenance gain ( 29064472 ) Refractive error ( 32231278 ) Risk-taking tendency (4-domain principal component model) ( 30643258 ) Smoking status (ever vs never smokers) ( 30643258 ) Squamous cell lung carcinoma ( 28604730 )
Interacting Genes		12 interacting genes: ATXN1 FXR1 G3BP1 ITCH LINC00624 MTNR1A MTNR1B NEDD4 PLXNA2 PRRC2A SUMO2 ZP3	6 interacting genes: CEMIP DHX37 FNBP4 HACE1 IFT80 UBAP2L
Entrez ID		9898	5362
HPRD ID		06665	03033
Ensembl ID		ENSG00000143569	ENSG00000076356
Uniprot IDs		A0AA34QVE6 B4DYY5 F8W726 Q14157	O75051
PDB IDs		Not available	3Q3J
GO Terms Enriched among Interactors		Melatonin Receptor Activity Cell Cortex	Positive Regulation Of Stress Granule Assembly Regulation Of Stress Granule Assembly Membraneless Organelle Assembly Organelle Assembly Macromolecule Catabolic Process Hyaluronan Biosynthetic Process Hyalurononglucosaminidase Activity Clathrin Heavy Chain Binding Positive Regulation Of Protein Kinase C Activity Positive Regulation Of Peptidyl-threonine Phosphorylation ER Retention Sequence Binding Nuclear Membrane Tooth Eruption Articular Cartilage Development Growth Plate Cartilage Chondrocyte Differentiation Protein Localization To Non-motile Cilium Protein Localization To Ciliary Membrane Growth Plate Cartilage Development 9+0 Non-motile Cilium Osteoblast Proliferation Negative Regulation Of Non-canonical Wnt Signaling Pathway Odontoblast Differentiation Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Bone Mineralization Involved In Bone Maturation Response To Inositol Cartilage Homeostasis Receptor Localization To Non-motile Cilium Positive Regulation Of Male Gonad Development U3 SnoRNA Binding Hyaluronan Catabolic Process