SEPTIN7 and S100A4

Number of citations: 0 (PubMedID 14531065)
Data Source: HPRD (in vitro)

		SEPTIN7	S100A4
Name		septin 7	S100 calcium binding protein A4
Structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Stress Fiber Nucleus Chromosome Cytoplasm Spindle Cytosol Cytoskeleton Cilium Axoneme Septin Ring Microtubule Cytoskeleton Apical Plasma Membrane Midbody Septin Complex Motile Cilium Cell Division Site Cleavage Furrow Cell Projection Extracellular Exosome Sperm Annulus Non-motile Cilium	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Extracellular Matrix Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Cadherin Binding Molecular Adaptor Activity	RNA Binding Actin Binding Calcium Ion Binding Protein Binding Chemoattractant Activity Identical Protein Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Spermatogenesis Intracellular Protein Localization Regulation Of Embryonic Cell Shape Cell Differentiation Cell Division Cilium Assembly Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly	Epithelial To Mesenchymal Transition Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Chemotaxis
Pathways		MAPK6/MAPK4 signaling	None
Drugs		None	Trifluoperazine Copper
GWAS		No GWAS studies recorded	Pulse pressure ( 30578418 )
Interacting Genes		15 interacting genes: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE GRIK1 HDAC6 LINC01554 OGT PCNT REL S100A4 SEPTIN11 SEPTIN5 SEPTIN9	29 interacting genes: ACTA1 ANXA2 BAG6 CCN3 CEP20 EGFR FCGR3A HSPB1 IFNB1 MDM2 METAP2 MYH10 MYH2 MYH4 MYH9 PPFIBP1 RHOU S100A1 S100B S100P SEPTIN2 SEPTIN6 SEPTIN7 SMAD3 SRPK2 TP53 TPM2 TPM3 UNC119
Entrez ID		989	6275
HPRD ID		04398	15914
Ensembl ID		ENSG00000122545	ENSG00000196154
Uniprot IDs		A0A023T695 A0A024RA87 A8K3D0 B4DNE4 G3V1Q4 Q16181	P26447
PDB IDs		2QAG 3T5D 3TW4 6N0B 6N12 6UQQ 7M6J 8SJJ	1M31 2LNK 2MRD 2Q91 3C1V 3CGA 3KO0 3M0W 3ZWH 4CFQ 4CFR 4ETO 4HSZ 5LPU 6T58 7PSP 7PSQ
GO Terms Enriched among Interactors		Microtubule Cytoskeleton Cytoskeleton Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Septin Ring Septin Complex Positive Regulation Of Pseudopodium Assembly Cell Division Site Positive Regulation Of Cell Projection Organization Cytoskeleton-dependent Cytokinesis Regulation Of Cell Projection Assembly Positive Regulation Of Cellular Component Biogenesis Septin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Molecular Adaptor Activity Regulation Of Protein-containing Complex Assembly Positive Regulation Of Protein-containing Complex Assembly Rho Protein Signal Transduction Cell Division Regulation Of Cell Morphogenesis Positive Regulation Of Protein Polymerization Membraneless Organelle Assembly Regulation Of Actin Filament Polymerization Microtubule Regulation Of Cell Shape Positive Regulation Of Cellular Component Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Organelle Assembly Regulation Of Supramolecular Fiber Organization Regulation Of Organelle Organization Cytoplasm Positive Regulation Of Supramolecular Fiber Organization Regulation Of Cellular Component Organization Positive Regulation Of Cytoskeleton Organization Intracellular Signaling Cassette Microtubule Plus-end Directed Mitotic Chromosome Migration Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Polyubiquitinated Misfolded Protein Transport Positive Regulation Of Cholangiocyte Proliferation Positive Regulation Of Organelle Organization Cytoskeletal Regulatory Protein Binding Septin Ring Assembly Regulation Of Cytoskeleton Organization Mitophagy Cytoskeleton Organization Regulation Of Cellular Component Size	Cytoplasm Identical Protein Binding Cleavage Furrow Actin Filament Binding Myosin II Complex Myosin Filament Spindle Sperm Annulus Stress Fiber Microfilament Motor Activity Cytoskeleton-dependent Cytokinesis Supramolecular Fiber Cytosol S100 Protein Binding Cell Division Site Septin Ring Septin Complex Cytoskeletal Motor Activity Myosin Complex Regulation Of Developmental Process Actin Filament-based Movement Regulation Of Cell Shape Cellular Response To Actinomycin D Myosin II Filament Calcium-dependent Protein Binding Cadherin Binding Cytoskeleton Supramolecular Fiber Organization Midbody Response To Actinomycin D Muscle Thin Filament Tropomyosin Muscle Contraction Regulation Of Protein Kinase C Signaling Cellular Response To UV-C Actin Binding ADP Binding Actin-mediated Cell Contraction Negative Regulation Of Protein Catabolic Process Regulation Of Cell Morphogenesis Regulation Of Plasma Membrane Repair Muscle System Process Nucleotide Binding Cell Adhesion Cellular Developmental Process System Process Actin Cytoskeleton Regulation Of Protein Localization Sarcomere Positive Regulation Of Gene Expression Regulation Of Protein Processing