SEPTIN7 and CDC42EP3

Number of citations: 0 (PubMedID 11584266)
Data Source: BioGRID (pull down)

		SEPTIN7	CDC42EP3
Name		septin 7	CDC42 effector protein 3
Structure			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Stress Fiber Nucleus Chromosome Cytoplasm Spindle Cytosol Cytoskeleton Cilium Axoneme Septin Ring Microtubule Cytoskeleton Apical Plasma Membrane Midbody Septin Complex Motile Cilium Cell Division Site Cleavage Furrow Cell Projection Extracellular Exosome Sperm Annulus Non-motile Cilium	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Actin Cytoskeleton Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Cadherin Binding Molecular Adaptor Activity	Protein Binding Cytoskeletal Regulatory Protein Binding Small GTPase Binding
	Biological Process	Spermatogenesis Intracellular Protein Localization Regulation Of Embryonic Cell Shape Cell Differentiation Cell Division Cilium Assembly Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly	Signal Transduction Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly
Pathways		MAPK6/MAPK4 signaling	MAPK6/MAPK4 signaling CDC42 GTPase cycle RHOQ GTPase cycle
GWAS		No GWAS studies recorded	Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Cortical surface area (min-P) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) Cortical thickness (MOSTest) ( 32665545 ) Cortical volume ( 32963231 ) Facial attractiveness (male raters) ( 30946739 ) HDL cholesterol levels in HIV infection ( 33109212 ) Height ( 31562340 28552196 23563607 20881960 ) Night sleep phenotypes ( 27126917 ) Rheumatoid arthritis ( 30891314 ) Subcortical volume (min-P) ( 32665545 ) Subcortical volume (MOSTest) ( 32665545 ) Total ventricular volume (Alzheimer's disease interaction) ( 21116278 ) Waist circumference adjusted for body mass index ( 34021172 ) Youthful appearance (self-reported) ( 32339537 )
Interacting Genes		15 interacting genes: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE GRIK1 HDAC6 LINC01554 OGT PCNT REL S100A4 SEPTIN11 SEPTIN5 SEPTIN9	12 interacting genes: CDC42 COPE DAPK1 LRRK1 LRRK2 MFHAS1 RHOQ SEPTIN6 SEPTIN7 SNCA SRPK1 UMPS
Entrez ID		989	10602
HPRD ID		04398	09364
Ensembl ID		ENSG00000122545	ENSG00000163171
Uniprot IDs		A0A023T695 A0A024RA87 A8K3D0 B4DNE4 G3V1Q4 Q16181	Q9UKI2
PDB IDs		2QAG 3T5D 3TW4 6N0B 6N12 6UQQ 7M6J 8SJJ	Not available
GO Terms Enriched among Interactors		Microtubule Cytoskeleton Cytoskeleton Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Septin Ring Septin Complex Positive Regulation Of Pseudopodium Assembly Cell Division Site Positive Regulation Of Cell Projection Organization Cytoskeleton-dependent Cytokinesis Regulation Of Cell Projection Assembly Positive Regulation Of Cellular Component Biogenesis Septin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Molecular Adaptor Activity Regulation Of Protein-containing Complex Assembly Positive Regulation Of Protein-containing Complex Assembly Rho Protein Signal Transduction Cell Division Regulation Of Cell Morphogenesis Positive Regulation Of Protein Polymerization Membraneless Organelle Assembly Regulation Of Actin Filament Polymerization Microtubule Regulation Of Cell Shape Positive Regulation Of Cellular Component Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Organelle Assembly Regulation Of Supramolecular Fiber Organization Regulation Of Organelle Organization Cytoplasm Positive Regulation Of Supramolecular Fiber Organization Regulation Of Cellular Component Organization Positive Regulation Of Cytoskeleton Organization Intracellular Signaling Cassette Microtubule Plus-end Directed Mitotic Chromosome Migration Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Polyubiquitinated Misfolded Protein Transport Positive Regulation Of Cholangiocyte Proliferation Positive Regulation Of Organelle Organization Cytoskeletal Regulatory Protein Binding Septin Ring Assembly Regulation Of Cytoskeleton Organization Mitophagy Cytoskeleton Organization Regulation Of Cellular Component Size	GTP Binding Nucleotide Binding GBD Domain Binding GTPase Activity Regulation Of Macrophage Activation Sperm Annulus Cytoskeleton Cytoplasm Cell Division Site Septin Ring Septin Complex Response To Type II Interferon Regulation Of SNARE Complex Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Identical Protein Binding Intracellular Signal Transduction Syntaxin-1 Binding Protein Serine Kinase Activity GTP Metabolic Process Synaptic Vesicle Protein Serine/threonine Kinase Activity Phosphate-containing Compound Metabolic Process Positive Regulation Of Endocytosis Positive Regulation Of Filopodium Assembly Regulation Of Synaptic Vesicle Recycling Endocytosis Midbody Molecular Adaptor Activity Protein Kinase Activity Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Organelle Organization Terminal Bouton Cellular Response To Oxidative Stress Magnesium Ion Binding Regulation Of Cell Projection Assembly Positive Regulation Of Cellular Component Organization Spindle Cleavage Furrow Import Into Cell Regulation Of Filopodium Assembly Postsynapse Kinase Activity DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Axon Terminus