| Name |
membrane associated guanylate kinase, WW and PDZ domain containing 2 |
adrenoceptor beta 1 |
| Structure |
|
|
| GO Annotations |
Cellular Component |
|
|
| Molecular Function |
|
|
| Biological Process |
|
|
| Pathways |
|
|
| Drugs |
None
|
|
| GWAS |
- Acute lymphoblastic leukemia (childhood) ( 23007406
)
- Adult body size ( 32376654
)
- Adverse response to drug ( 30420678
)
- Airway wall thickness ( 25517131
)
- Bitter beverage consumption ( 31046077
)
- Body mass index ( 25673413
28892062
)
- Body size at age 10 ( 32376654
)
- Bronchopulmonary dysplasia ( 23897914
)
- Chronotype ( 30696823
)
- Computer vision syndrome ( 33941792
)
- Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444
)
- Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444
)
- General risk tolerance (MTAG) ( 30643258
)
- Hippocampal atrophy ( 19668339
)
- Itch intensity from mosquito bite adjusted by bite size ( 28199695
)
- LDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535
)
- LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535
)
- Lead levels in blood ( 25820613
)
- Low density lipoprotein cholesterol levels ( 33339817
)
- Mammographic density (dense area) ( 25342443
)
- Memory dysfunction in frontotemporal lobe dementia ( 29724592
)
- Metabolite levels ( 23823483
)
- Nicotine dependence ( 33144568
)
- Night sleep phenotypes ( 27126917
)
- Obesity-related traits ( 23251661
)
- Pursuit maintenance gain ( 29064472
)
- Refractive error ( 32231278
)
- Response to anti-depressant treatment in major depressive disorder ( 22041458
)
- Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125
)
- Schizophrenia ( 30285260
28991256
)
- Serum folate levels ( 29953918
)
- Total cholesterol levels ( 33339817
)
- Visceral fat ( 30942860
)
|
- Apolipoprotein A1 levels ( 32203549
)
- Apolipoprotein B levels ( 32203549
)
- Aspartate aminotransferase levels ( 33547301
)
- Birth weight ( 23202124
31043758
27680694
)
- Blood pressure ( 21909110
)
- Diastolic blood pressure ( 27618452
27841878
28135244
28739976
)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858
)
- Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962
)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962
)
- Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858
)
- Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858
)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098
)
- Gaucher disease severity ( 22388998
)
- HDL cholesterol levels ( 32203549
)
- High density lipoprotein cholesterol levels ( 29083408
)
- LDL cholesterol levels ( 32203549
)
- Lipid traits (pleiotropy) (HIPO component 1) ( 30289880
)
- Mean arterial pressure ( 27618448
)
- Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962
)
- Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962
)
- Medication use (agents acting on the renin-angiotensin system) ( 31015401
)
- Medication use (diuretics) ( 31015401
)
- Offspring birth weight ( 31043758
)
- Platelet distribution width ( 32888494
)
- PR interval ( 32439900
)
- Systolic blood pressure ( 27618447
30578418
27618452
27841878
28739976
)
- Systolic blood pressure (cigarette smoking interaction) ( 29455858
)
- Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962
)
- Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962
)
- Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858
)
- Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858
)
- Triglyceride levels ( 32203549
)
|
| Interacting Genes |
30 interacting genes:
ACVR2A
ADGRB1
ADRB1
ARRDC3
ATN1
CRHR1
CTNNB1
CTNND2
DLGAP1
DLGAP2
DLGAP3
DLL1
DSCAM
DSCAML1
DYRK3
GRID2
LCOR
MORN4
PDZD11
PLEKHF2
PLXNB3
PRRG4
PTEN
RAPGEF2
RIPK4
RPS6KA1
SMAD3
SNRPB
TGFA
VANGL2
|
17 interacting genes:
ADRA2A
ADRB2
ARRB1
DLG1
DLG4
DLGAP2
GIPC1
GOPC
GPRASP1
GPRASP2
GRB2
MAGI2
MAGI3
NOS1
SH3GL2
SH3GL3
SNTA1
|
| Entrez ID |
9863 |
153 |
| HPRD ID |
16212
|
00181
|
| Ensembl ID |
ENSG00000187391
|
ENSG00000043591
|
| Uniprot IDs |
B7Z4H4
Q86UL8
|
P08588
|
| PDB IDs |
1UEP
1UEQ
1UEW
1UJV
1WFV
|
2LSQ
7BTS
7BU6
7BU7
7BVQ
|
| GO Terms Enriched among Interactors |
|
|