CDK11B and CCNL2

Number of citations: 0 (PubMedID 14684736)
Data Source: HPRD (in vivo)

		CDK11B	CCNL2
Name		cyclin dependent kinase 11B	cyclin L2
Structure			No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Nucleotide Binding RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process	Mitotic Cell Cycle Regulation Of Cell Growth Regulation Of DNA-templated Transcription Protein Phosphorylation Apoptotic Process Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Centrosome Cycle Regulation Of MRNA Processing Regulation Of Cell Cycle	Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Centrosome Cycle Regulation Of Cell Cycle
Pathways		Recruitment of mitotic centrosome proteins and complexes	None
GWAS		Body mass index ( 26426971 )	Inflammatory bowel disease ( 28067908 ) Ulcerative colitis ( 28067908 )
Interacting Genes		26 interacting genes: AP2M1 CASP1 CASP3 CASP8 CCND3 CCNL2 CHEK2 EIF3F H1-1 KAT7 MSN PAK1 PDE4B PIN1 RANBP9 RNF10 RPS27A TCEA2 TH TPPP URM1 YWHAB YWHAE YWHAG YWHAQ YWHAZ	15 interacting genes: CDK11B DYRK1A EMD FAM90A1 KRTAP12-2 MAGEB2 MDFI PIH1D2 POLR2A RUNDC3A SRSF2 SRSF7 TRIM41 USP20 ZBTB7B
Entrez ID		984	81669
HPRD ID		08909	10815
Ensembl ID		ENSG00000248333	ENSG00000221978
Uniprot IDs		B4DII1 P21127	Q96S94
PDB IDs		7UKZ	Not available
GO Terms Enriched among Interactors		Phosphoserine Residue Binding Protein Targeting Protein Sequestering Activity Cytosol Nucleus Transmembrane Transporter Binding Focal Adhesion Regulation Of Protein Localization Vesicle Protein Modification Process Cytoplasm Protein Domain Specific Binding Enzyme Binding Post-translational Protein Modification Phosphoprotein Binding Identical Protein Binding Response To Anesthetic Regulation Of Primary Metabolic Process Pyroptotic Inflammatory Response Regulation Of Macromolecule Metabolic Process Cysteine-type Peptidase Activity Death-inducing Signaling Complex Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Immune System Process Positive Regulation Of Pyroptotic Inflammatory Response Ubiquitin Protein Ligase Binding Regulation Of Protein Localization To Nucleus Response To Cobalt Ion Cysteine-type Endopeptidase Activity Negative Regulation Of Intracellular Signal Transduction Regulation Of Metabolic Process Protein Metabolic Process Regulation Of System Process Negative Regulation Of Signal Transduction Interleukin-18-mediated Signaling Pathway Intracellular Signal Transduction Protein Tag Activity Regulation Of Protein Stability Protein Catabolic Process Immune System Process Proteolysis Death Receptor Binding Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Poly-ADP-ribosylation Response To Starvation Positive Regulation Of Myelination Cellular Response To Stress Regulation Of Gene Expression Microtubule Polymerization	Regulation Of RNA Splicing Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of RNA Splicing Negative Regulation Of RNA Metabolic Process Histone H3T45 Kinase Activity TMEM240-body Negative Regulation Of NK T Cell Proliferation