ZSCAN12 and ZNF473

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		ZSCAN12	ZNF473
Name		zinc finger and SCAN domain containing 12	zinc finger protein 473
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cajal Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II MRNA 3'-end Processing By Stem-loop Binding And Cleavage
Pathways		None	SLBP independent Processing of Histone Pre-mRNAs Generic Transcription Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
GWAS		Asthma and major depressive disorder ( 31619474 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Brain morphology (MOSTest) ( 32665545 ) Chronic obstructive pulmonary disease ( 33909500 ) Fish- and plant-related diet ( 32066663 ) Lung cancer ( 28604730 ) Refractive error ( 32231278 ) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848 ) Sleep duration (short sleep) ( 30846698 ) Smoking initiation (ever regular vs never regular) ( 30679032 ) Squamous cell lung carcinoma ( 28604730 ) Subcortical volume (MOSTest) ( 32665545 )	No GWAS studies recorded
Interacting Genes		26 interacting genes: BICD2 CENPH CEP70 FAM161A KRTAP10-1 KRTAP10-8 LMNA MID2 MTUS2 PGBD1 RACK1 SCAND1 SRPK2 SSX2IP TFIP11 VCX VLDLR VPS26A ZKSCAN7 ZNF24 ZNF397 ZNF446 ZNF473 ZNF496 ZSCAN21 ZSCAN32	22 interacting genes: AEN APP CLK2 CLK3 DHX57 GPATCH2L KRTAP10-10 KRTAP10-8 KRTAP10-9 LSM11 PRPF31 RBM10 RNPS1 SLBP TRIM41 ZNF202 ZNF250 ZNF408 ZNF497 ZNF792 ZNF837 ZSCAN12
Entrez ID		9753	25888
HPRD ID		15767	11721
Ensembl ID		ENSG00000158691	ENSG00000142528
Uniprot IDs		A0A804HJ42 O43309	B4DY71 F8WEC7 Q8WTR7
PDB IDs		Not available	2EMB 2EMC 2EME 2EOU 2EOX 2EOY 2EOZ 2YRH 2YRJ 2YSV 2YTD 2YTE 2YTT 2YU5 9AZI
GO Terms Enriched among Interactors		None	Identical Protein Binding PTB Domain Binding Nucleus MRNA 3'-end Processing By Stem-loop Binding And Cleavage Histone Pre-mRNA 3'end Processing Complex Regulation Of RNA Splicing Zinc Ion Binding Nuclear Speck RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding MRNA Processing Keratin Filament Negative Regulation Of MRNA Splicing, Via Spliceosome Histone MRNA Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Gene Expression Positive Regulation Of Toll Signaling Pathway Protein Serine/threonine/tyrosine Kinase Activity RNA Processing MRNA 3'-end Processing MRNA Metabolic Process Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Ribosomal Large Subunit Export From Nucleus Negative Regulation Of RNA Splicing Ribonucleoprotein Complex Localization Intermediate Filament Ribonucleoprotein Complex