IGSF8 and CD82

Number of citations: 0 (PubMedID 12750295)
Data Source: HPRD (in vitro)

		IGSF8	CD82
Name		immunoglobulin superfamily member 8	CD82 molecule
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Presynaptic Membrane Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse	Plasma Membrane Membrane Cytoplasmic Vesicle Phagocytic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Signaling Receptor Activity	Protein Binding
	Biological Process	Single Fertilization Nervous System Development Skeletal Muscle Tissue Development Positive Regulation Of Cell Migration Cell Motility Regulation Of Cell Motility	None
GWAS		No GWAS studies recorded	Blond vs. brown/black hair color ( 30531825 ) Cadmium levels ( 26025379 ) Hemostatic factors and hematological phenotypes ( 22443383 ) High light scatter reticulocyte count ( 27863252 32888494 ) High light scatter reticulocyte percentage of red cells ( 27863252 32888494 ) Lymphocyte count ( 32888494 ) Male-pattern baldness ( 27182965 ) Mean reticulocyte volume ( 32888494 ) Plasma parathyroid hormone levels ( 30134803 ) Red cell distribution width ( 27863252 28957414 32888494 ) Reticulocyte count ( 32888494 ) Reticulocyte fraction of red cells ( 32888494 ) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355 ) TNF-alpha gene expression levels in non-alcoholic fatty liver disease x mastiha supplementation interaction ( 34025683 )
Interacting Genes		18 interacting genes: A2M CD81 CD82 CD9 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-4 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-12 KRTAP5-7 NBPF19 NOTCH2NLA TGM1	29 interacting genes: BDKRB2 BRCC3 CANX CD19 CD4 CD63 CHRM5 CREB3 EGFR ERBB2 ERBB3 FFAR2 HBEGF HLA-DMA HLA-DMB HLA-DRA IGSF8 ITGA3 ITGA4 ITGA6 ITGB1 ITGB2 KLRC1 LRP1 NLRP3 NUP88 PTGFRN SMIM3 VANGL1
Entrez ID		93185	3732
HPRD ID		09438	09004
Ensembl ID		ENSG00000162729	ENSG00000085117
Uniprot IDs		Q969P0	P27701
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Keratin Filament Intermediate Filament Myoblast Fusion Involved In Skeletal Muscle Regeneration Cellular Response To Lipoprotein Particle Stimulus Myoblast Fusion Regulation Of Mononuclear Cell Migration Cell-cell Fusion Cellular Response To Low-density Lipoprotein Particle Stimulus Syncytium Formation Syncytium Formation By Plasma Membrane Fusion Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Regulation Of Macrophage Migration	Cell Surface Receptor Complex Integrin Complex Cell Surface Receptor Signaling Pathway Membrane Positive Regulation Of Cell Adhesion Regulation Of Multicellular Organismal Process Signaling Receptor Activity Cell-matrix Adhesion Regulation Of Cell Adhesion ERBB2 Signaling Pathway Immune System Process MHC Class II Protein Complex Binding Regulation Of Leukocyte Cell-cell Adhesion Cell-substrate Adhesion ERBB2-EGFR Signaling Pathway Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Immune System Process Integrin-mediated Signaling Pathway Signal Transduction Positive Regulation Of Immune Response Positive Regulation Of Cell-cell Adhesion Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation Plasma Membrane Peptide Antigen Assembly With MHC Class II Protein Complex Regulation Of Cell Migration ERBB3:ERBB2 Complex MHC Class II Protein Complex Integrin Alpha6-beta1 Complex Integrin Alpha3-beta1 Complex Coreceptor Activity Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Motility Regulation Of Immune System Process Cell Motility Positive Regulation Of Locomotion Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Immune Effector Process Focal Adhesion Clathrin-coated Endocytic Vesicle Membrane Regulation Of Locomotion Regulation Of Intracellular Signal Transduction Regulation Of Cell Activation Integrin Alpha4-beta1 Complex ERBB Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Localization To Cell Periphery