FCMR and HOXD9

Number of citations: 41 (PubMedID 20211142)
Data Source: BioGRID (two hybrid)

		FCMR	HOXD9
Name		Fc mu receptor	homeobox D9
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Lysosome Lysosomal Membrane Endosome Golgi Apparatus Centrosome Plasma Membrane Membrane Early Endosome Membrane Trans-Golgi Network Membrane	Chromatin Nucleus Nucleoplasm Nucleolus
	Molecular Function	Polymeric Immunoglobulin Binding IgM Binding High-affinity IgM Receptor Activity Transmembrane Signaling Receptor Activity Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Immune System Process Immunoglobulin Transcytosis In Epithelial Cells Humoral Immune Response Mediated By Circulating Immunoglobulin Cellular Defense Response Signal Transduction Fc Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Regulation Of B Cell Receptor Signaling Pathway Fc Receptor-mediated Immune Complex Endocytosis	Negative Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Single Fertilization Skeletal Muscle Tissue Development Adult Locomotory Behavior Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Regulation Of Gene Expression Mammary Gland Development Embryonic Forelimb Morphogenesis Forelimb Morphogenesis Hindlimb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development Peripheral Nervous System Neuron Development
GWAS		No GWAS studies recorded	Estimated glomerular filtration rate ( 31015462 ) Magnesium levels ( 20700443 ) Male-pattern baldness ( 28196072 )
Interacting Genes		3 interacting genes: ANKRD2 HOXD9 ZNHIT3	9 interacting genes: BARX1 ETV5 FCMR GORAB HMGB1 HOXC9 MEIS1 PBX1 PKNOX1
Entrez ID		9214	3235
HPRD ID		09349	00865
Ensembl ID		ENSG00000162894	ENSG00000128709
Uniprot IDs		O60667	P28356
PDB IDs		7YSG 7YTC 7YTD 7YTE 8BPE 8BPF 8BPG	Not available
GO Terms Enriched among Interactors		None	Eye Development Sensory Organ Development Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity DNA Binding Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Sequence-specific DNA Binding Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Hemopoiesis Regulation Of Neuron Differentiation Sequence-specific Double-stranded DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Spleen Development Transcription Regulator Complex Lymphocyte Differentiation Transcription Cis-regulatory Region Binding Regulation Of RNA Metabolic Process Regionalization Embryonic Skeletal System Development Animal Organ Development Developmental Process Regulation Of Nucleobase-containing Compound Metabolic Process Mononuclear Cell Differentiation Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Transcription Repressor Complex Positive Regulation Of Myeloid Progenitor Cell Differentiation High-affinity IgM Receptor Activity Negative Regulation Of Neuron Differentiation RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Cell Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Leukocyte Differentiation Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Negative Regulation Of Apoptotic Cell Clearance RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Polymeric Immunoglobulin Binding Cellular Developmental Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process DNA-templated Transcription Hematopoietic Or Lymphoid Organ Development Male Germ-line Stem Cell Asymmetric Division