SLC16A7 and SNTA1

Number of citations: 0 (PubMedID 15123239)
Data Source: BioGRID (unspecified method)

		SLC16A7	SNTA1
Name		solute carrier family 16 member 7	syntrophin alpha 1
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Basolateral Plasma Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Postsynaptic Density Membrane Glutamatergic Synapse	Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Syntrophin Complex Membrane Lateral Plasma Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Anchoring Junction
	Molecular Function	Pyruvate Secondary Active Transmembrane Transporter Activity Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Symporter Activity Secondary Active Monocarboxylate Transmembrane Transporter Activity Transmembrane Transporter Activity Identical Protein Binding Pyruvate Transmembrane Transporter Activity	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Transmembrane Transporter Binding Nitric-oxide Synthase Binding ATPase Binding
	Biological Process	Monocarboxylic Acid Transport Lactate Transmembrane Transport Plasma Membrane Lactate Transport Transmembrane Transport Transport Across Blood-brain Barrier Pyruvate Transmembrane Transport	Regulation Of Heart Rate Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport
Pathways		Proton-coupled monocarboxylate transport	Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs		Pyruvic acid	None
Diseases		None	Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS		Adventurousness ( 30643258 ) Calcium levels ( 25972035 ) General risk tolerance (MTAG) ( 30643258 ) Hematocrit ( 29403010 ) Kawasaki disease ( 33692975 ) Logical memory (delayed recall) in normal cognition ( 29274321 ) Logical memory (immediate recall) in normal cognition ( 29274321 ) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901 ) Takayasu arteritis ( 25604533 )	HDL cholesterol x physical activity interaction (1df test) ( 30670697 ) HDL cholesterol x physical activity interaction (2df test) ( 30670697 )
Interacting Genes		15 interacting genes: ACSL5 CDIPT COMT CPEB1 FXYD6 GPR25 HMOX1 IFITM3 LEMD1 SFXN1 SMAGP SNTA1 TIMM23 VAPA VTI1B	76 interacting genes: ABCA1 ABCC4 ACTA2 ADAMTS6 ADGRB1 ADGRB2 ADGRB3 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA DTNB ENTREP3 F8A1 FABP1 GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 RPS6KA1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TIAM1 TLX3 TRA TRBV12-3 UTRN VANGL2 XRCC6
Entrez ID		9194	6640
HPRD ID		06791	03009
Ensembl ID		ENSG00000118596	ENSG00000101400
Uniprot IDs		O60669	B3KTR0 Q13424
PDB IDs		7BP3	Not available
GO Terms Enriched among Interactors		Membrane	Plasma Membrane System Process Regulation Of System Process Membrane G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Activity Regulation Of Blood Circulation Circulatory System Process Vascular Process In Circulatory System Monoatomic Ion Channel Complex Regulation Of Multicellular Organismal Process Regulation Of Heart Contraction Blood Vessel Diameter Maintenance Regulation Of Tube Size Basolateral Plasma Membrane Monoatomic Ion Transmembrane Transport Regulation Of Biological Quality Transmembrane Transport Muscle Contraction Inorganic Ion Transmembrane Transport Metal Ion Transport Monoatomic Ion Transport Regulation Of Heart Rate Inorganic Cation Transmembrane Transport Regulation Of Membrane Potential Monoatomic Cation Transmembrane Transport Monoatomic Cation Transport Cardiac Muscle Cell Action Potential Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Muscle System Process Synapse Inward Rectifier Potassium Channel Activity Synaptic Signaling Vasodilation Intracellular Signaling Cassette Regulation Of Monoatomic Ion Transmembrane Transport Adrenergic Receptor Activity CGMP-mediated Signaling Calcium-mediated Signaling Action Potential Potassium Ion Transport Regulation Of Blood Pressure Regulation Of Muscle Contraction Regulation Of Monoatomic Ion Transport Voltage-gated Sodium Channel Complex Signal Transduction Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Multicellular Organismal Process