AP5B1 and KCNRG

Number of citations: 0 (PubMedID 16189514)
Data Source: HPRD (two hybrid)

		AP5B1	KCNRG
Name		adaptor related protein complex 5 subunit beta 1	potassium channel regulator
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Late Endosome AP-type Membrane Coat Adaptor Complex AP-5 Adaptor Complex	Endoplasmic Reticulum
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Transport Vesicle-mediated Transport Endosomal Transport	Protein Homooligomerization Negative Regulation Of Delayed Rectifier Potassium Channel Activity
GWAS		Acne (severe) ( 24927181 ) Albumin-globulin ratio ( 29403010 ) Allergic disease (asthma, hay fever or eczema) ( 29083406 ) Asthma ( 34103634 31619474 31361310 30929738 ) Asthma (age of onset) ( 31036433 ) Asthma (childhood onset) ( 30929738 31036433 ) Asthma onset (childhood vs adult) ( 30929738 ) Atopic march ( 26542096 ) Blood urea nitrogen levels ( 31152163 ) Chronic kidney disease ( 31152163 ) Creatinine levels ( 29403010 ) Eczema ( 31361310 ) Glomerular filtration rate (creatinine) ( 26831199 ) Gout ( 33832965 ) Parental longevity (combined parental attained age, Martingale residuals) ( 29227965 ) Psoriasis ( 25854761 ) Refractive error ( 32231278 ) Spherical equivalent or myopia (age of diagnosis) ( 29808027 ) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858 ) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858 ) White matter hyperintensity volume ( 33293549 )	Aortic root size ( 28394258 ) Height ( 25282103 ) Type 2 diabetes ( 30718926 )
Interacting Genes		6 interacting genes: CALCOCO2 CFTR KCNRG MAP1LC3A NIF3L1 PDLIM7	5 interacting genes: AP5B1 CCNK DGCR6L FXR2 RFPL4A
Entrez ID		91056	283518
HPRD ID		13223	06404
Ensembl ID		ENSG00000254470	ENSG00000198553
Uniprot IDs		Q2VPB7	Q8N5I3
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Regulation Of Transmembrane Transporter Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Monoatomic Ion Transmembrane Transporter Activity Autophagosome Autophagosome Membrane Positive Regulation Of Anion Channel Activity Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Macroautophagy Cellular Response To Oxygen-glucose Deprivation Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Xenophagy Positive Regulation Of Autophagosome Maturation Response To Iron(II) Ion Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Voltage-gated Potassium Channel Activity Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Cellular Response To Nitrogen Starvation Regulation Of Delayed Rectifier Potassium Channel Activity Response To Oxygen-glucose Deprivation Regulation Of Monoatomic Anion Transport Regulation Of Monoatomic Ion Transmembrane Transport Epithelial Fluid Transport Autophagy Autolysosome Golgi-associated Vesicle Membrane Phosphatidylethanolamine Binding Cellular Response To Forskolin Muscle Alpha-actinin Binding Regulation Of Autophagosome Maturation Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Response To Lead Ion	Cyclin K-CDK13 Complex Cyclin K-CDK12 Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission AP-5 Adaptor Complex AP-type Membrane Coat Adaptor Complex Cyclin/CDK Positive Transcription Elongation Factor Complex