CLDN8 and CLEC17A

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		CLDN8	CLEC17A
Name		claudin 8	C-type lectin domain containing 17A
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Bicellular Tight Junction Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Anchoring Junction	External Side Of Plasma Membrane Cell Surface Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Protein Binding D-mannose Binding Carbohydrate Binding Pattern Recognition Receptor Activity Identical Protein Binding Fucose Binding Metal Ion Binding
	Biological Process	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly	Immune Response
Pathways		Tight junction interactions	None
GWAS		Response to statin therapy ( 20339536 )	Femur bone mineral density x serum urate levels interaction ( 34046847 ) Iris color (L* coordinate) ( 30895295 ) Low density lipoprotein cholesterol levels ( 33339817 ) Response to antidepressants (symptom improvement) ( 29160301 ) Total cholesterol levels ( 33339817 )
Interacting Genes		12 interacting genes: ADAM32 ARL13B CLEC17A ERGIC3 KASH5 OPRM1 PKMYT1 SMIM3 SYNE4 TJP1 TMEM80 TRARG1	21 interacting genes: ASGR2 ATP6V0C CLDN8 CTXN3 CXCL9 FAM3C GPR152 IGFBP5 NCK2 NINJ2 OLFM4 PELI1 PELI2 RPRM SEC23A SMIM3 TM4SF4 TMEM140 TMEM201 TMEM218 UPK2
Entrez ID		9073	388512
HPRD ID		10835	16993
Ensembl ID		ENSG00000156284	ENSG00000187912
Uniprot IDs		A0A0K0K1I9 P56748	Q6ZS10
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Nuclear Outer Membrane	Regulation Of Toll Signaling Pathway