SYT7 and STX2

Number of citations: 0 (PubMedID 7791877)
Data Source: HPRD (in vitro)

		SYT7	STX2
Name		synaptotagmin 7	syntaxin 2
Structure			No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Peroxisome Peroxisomal Membrane Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Axon Transport Vesicle Membrane Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Dense Core Granule Cytoplasmic Vesicle Early Phagosome Presynaptic Membrane Cell Projection Synapse Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse Secretory Vesicle	Extracellular Space Plasma Membrane Endomembrane System Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Protein-containing Complex Intracellular Membrane-bounded Organelle Presynaptic Active Zone Membrane
	Molecular Function	SNARE Binding Calcium Ion Binding Protein Binding Calmodulin Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Syntaxin Binding Clathrin Binding Metal Ion Binding Calcium Ion Sensor Activity	SNARE Binding Structural Molecule Activity SNAP Receptor Activity Protein Binding Identical Protein Binding Calcium-dependent Protein Binding
	Biological Process	Plasma Membrane Repair Exocytosis Vesicle Fusion Phagocytosis Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Endocytosis Synaptic Vesicle Recycling Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Bone Remodeling Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Phagocytosis Regulation Of Insulin Secretion Positive Regulation Of Transport Regulation Of Glucagon Secretion Vesicle-mediated Cholesterol Transport Phagosome-lysosome Fusion Calcium-dependent Activation Of Synaptic Vesicle Fusion Regulation Of Synaptic Vesicle Endocytosis Short-term Synaptic Potentiation Calcium Ion Regulated Lysosome Exocytosis	Intracellular Protein Transport Exocytosis Signal Transduction Acrosome Reaction Ectoderm Development Animal Organ Morphogenesis Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress Vesicle Docking Cornified Envelope Assembly
Pathways		Neurexins and neuroligins	None
GWAS		Intelligence (MTAG) ( 29326435 ) Mean arterial pressure ( 26390057 ) Metabolite levels ( 23823483 ) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311 ) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311 )	Initial pursuit acceleration in psychotic disorders ( 29064472 ) Metabolite levels ( 23823483 ) Plasma plasminogen activator levels ( 24578379 ) vWF levels ( 30586737 )
Interacting Genes		8 interacting genes: AP2A1 NRXN1 SIAH1 STX1A STX2 STX3 STX4 SYNCRIP	65 interacting genes: AARD ABI3 ANKRD46 APOL2 BET1 BLOC1S2 CD53 CDC23 CERT1 CPLX2 CTSA CYBC1 EBAG9 ENTPD3 FGA GET1 GIMAP5 MIP MRPL11 MTG1 NAPB NINJ2 PCGF2 PLN PLPP4 RMDN3 RNF4 RTP2 SEC22A SEC22B SERP1 SLC18A1 SNAP25 SNAP29 SNCA STRIT1 STX12 STX16 STX1A STX1B STX3 STX4 STX5 STX6 STX7 STX8 STXBP1 STXBP2 STXBP5L SYT1 SYT4 SYT7 TMEM120A TMEM120B TSPAN8 UBE2I UNC13B VAMP2 VAMP3 VAMP5 VAPB VTI1B ZCCHC12 ZFPL1 ZNF785
Entrez ID		9066	2054
HPRD ID		11965	11816
Ensembl ID		ENSG00000011347	ENSG00000111450
Uniprot IDs		O43581	A0A994J5V9 A0A994J840 P32856
PDB IDs		2D8K	Not available
GO Terms Enriched among Interactors		SNAP Receptor Activity SNARE Complex SNARE Binding Vesicle Docking Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Neurotransmitter Transport Organelle Membrane Fusion Organelle Fusion Positive Regulation Of Synaptic Transmission Secretion By Cell Membrane Fusion Organelle Localization Exocytosis Secretion Membrane Assembly Intracellular Protein Transport Cornified Envelope Assembly Glutamatergic Synapse Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Endomembrane System Calcium-dependent Protein Binding Positive Regulation Of Protein Localization To Cell Periphery Membrane Organization Positive Regulation Of Protein Localization To Membrane Establishment Of Protein Localization Vesicle-mediated Transport In Synapse Vesicle Organization Schaffer Collateral - CA1 Synapse SNARE Complex Assembly Specific Granule Regulation Of Protein Localization To Plasma Membrane Cellular Localization Establishment Of Localization In Cell Vacuole Positive Regulation Of Protein Localization To Cell Surface Regulation Of Biological Quality Regulation Of Protein Localization To Cell Periphery Intracellular Protein Localization Modulation Of Chemical Synaptic Transmission Regulation Of Protein Localization To Membrane Presynaptic Active Zone Membrane Protein Transport Lamellipodium Positive Regulation Of Excitatory Postsynaptic Potential Vesicle-mediated Transport Intracellular Transport Synaptic Vesicle Endocytosis	SNAP Receptor Activity SNARE Complex Organelle Localization By Membrane Tethering SNARE Binding Membrane Docking Vesicle Docking Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Organelle Fusion Vesicle Organization Membrane Organization Organelle Localization Syntaxin Binding Vesicle-mediated Transport Establishment Of Localization In Cell Synaptic Vesicle Exocytosis Exocytosis Calcium-ion Regulated Exocytosis Cellular Localization Syntaxin-1 Binding Secretion By Cell Regulated Exocytosis Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport In Synapse Neurotransmitter Transport Calcium Ion-regulated Exocytosis Of Neurotransmitter Establishment Of Protein Localization Intracellular Transport Protein Transport Secretion Endomembrane System Signal Release SNARE Complex Assembly Synaptic Vesicle Membrane Membrane Regulation Of Exocytosis Regulation Of Secretion By Cell Regulation Of Synaptic Vesicle Priming Regulation Of Secretion Positive Regulation Of Exocytosis Intracellular Protein Transport Vesicle Intracellular Protein Localization Synaptic Vesicle Neuronal Dense Core Vesicle Exocytosis Regulation Of Vesicle Fusion Positive Regulation Of Synaptic Transmission Synaptic Vesicle Priming Positive Regulation Of Calcium Ion-dependent Exocytosis