CCNG2 and NRIP2

Number of citations: 38 (PubMedID 21988832)
Data Source: BioGRID (two hybrid)

		CCNG2	NRIP2
Name		cyclin G2	nuclear receptor interacting protein 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	Aspartic-type Endopeptidase Activity Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Cell Division Regulation Of Cell Cycle	Negative Regulation Of Transcription By RNA Polymerase II Proteolysis Notch Signaling Pathway
Pathways		FOXO-mediated transcription of cell cycle genes	None
GWAS		Hormone measurements ( 30576415 )	No GWAS studies recorded
Interacting Genes		7 interacting genes: EFHC2 NRIP2 PPP2CA PTPA TASOR2 TCF7L2 ZNF410	8 interacting genes: AKT1 BANP CCNG2 ELF5 HDAC7 RARA RORB ZNF76
Entrez ID		901	83714
HPRD ID		04438	14839
Ensembl ID		ENSG00000138764	ENSG00000053702
Uniprot IDs		Q16589	Q9BQI9
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Protein Phosphatase Type 2A Complex Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Small Molecule Metabolic Process RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Negative Regulation Of Metabolic Process RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Phosphoprotein Phosphatase Activity Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Negative Regulation Of Wnt Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Protein Tyrosine Phosphatase Activator Activity Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Beta-catenin-TCF7L2 Complex Catenin-TCF7L2 Complex Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Proteoglycan Biosynthetic Process Myoblast Fate Commitment Phosphatase Activator Activity Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Maintenance Of DNA Repeat Elements Armadillo Repeat Domain Binding Protein Serine/threonine Phosphatase Complex Peptidyl-threonine Dephosphorylation	Mammary Gland Epithelial Cell Differentiation Sequence-specific DNA Binding 14-3-3 Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Sequence-specific Double-stranded DNA Binding Regulation Of Transcription By RNA Polymerase II Intracellular Receptor Signaling Pathway Regulation Of Myelination Negative Regulation Of Cell Differentiation Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of RNA Biosynthetic Process Striated Muscle Cell Differentiation Regulation Of Cell Differentiation Nucleus Regulation Of TRNA Methylation Positive Regulation Of DNA-templated Transcription Sertoli Cell Fate Commitment Nuclear Receptor Activity Cellular Response To Retinoic Acid Negative Regulation Of Osteoblast Differentiation Positive Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Protein Localization To Lysosome DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Ectodermal Cell Fate Commitment DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cellular Response To Lipid Response To Retinoic Acid Positive Regulation Of Protein Localization To Endoplasmic Reticulum Regulation Of RNA Metabolic Process Response To Insulin-like Growth Factor Stimulus Regulation Of Blood Vessel Endothelial Cell Migration Mammalian Oogenesis Stage TRNA (guanine-N7)-methylation Muscle Cell Differentiation Positive Regulation Of Endothelial Cell Migration Cellular Response To Rapamycin Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Endodeoxyribonuclease Activity DNA Binding Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane TORC2 Complex Binding Positive Regulation Of Deoxyribonuclease Activity Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process SREBP-SCAP Complex Retention In Endoplasmic Reticulum Trachea Cartilage Development