UBL7 and VBP1

Number of citations: 97 (PubMedID 33961781)
Data Source: BioGRID (two hybrid, affinity chromatography technology)

		UBL7	VBP1
Name		ubiquitin like 7	VHL binding protein 1
Structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Cytoplasm Cytosol Prefoldin Complex Protein-containing Complex
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity Polyubiquitin Modification-dependent Protein Binding	Amyloid-beta Binding Protein Binding Tubulin Binding Unfolded Protein Binding
	Biological Process	Immune System Process Ubiquitin-dependent Protein Catabolic Process Protein K27-linked Ubiquitination Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response	Protein Folding Microtubule-based Process Tubulin Complex Assembly Negative Regulation Of Amyloid Fibril Formation
Pathways		None	Prefoldin mediated transfer of substrate to CCT/TriC
GWAS		Craniofacial microsomia ( 26853712 ) Eosinophil percentage of white cells ( 32888494 ) Itch intensity from mosquito bite adjusted by bite size ( 28199695 ) Metabolite levels ( 23823483 )	No GWAS studies recorded
Interacting Genes		17 interacting genes: AP1G1 BAG6 CAPN7 CD4 CDKN2A ERCC1 ESRRG IDH1 MFHAS1 MYBPH NEDD8 RAD23A RXRB SH3GLB1 UBC VBP1 WWP2	31 interacting genes: AIRIM DDIT4L EFHC1 ENKD1 FGF1 GLIS2 GPANK1 HIF1A IKZF3 LMO1 LMO2 LMO3 MEOX2 MISP MKNK2 MSH4 MYOZ1 PFDN2 PIK3R3 PNMA1 PRKAB2 SUOX TCEANC TSC22D4 UBC UBL7 VEZF1 VHL XRCC6 ZNF410 ZNF576
Entrez ID		84993	7411
HPRD ID		16556	02135
Ensembl ID		ENSG00000138629	ENSG00000155959
Uniprot IDs		Q96S82	P61758 Q6FH24
PDB IDs		2CWB 2DEN	6NR8 6NR9 6NRB 6NRC 6NRD 7WU7
GO Terms Enriched among Interactors		Replicative Senescence Retinoic Acid Receptor Signaling Pathway Nuclear Steroid Receptor Activity Ubiquitin Protein Ligase Binding Modification-dependent Protein Catabolic Process Protein Tag Activity Proteasome Binding Ubiquitin-specific Protease Binding Macromolecule Catabolic Process Regulation Of Protein Stability Proteolysis Involved In Protein Catabolic Process Regulation Of Proteolysis Regulation Of Ubiquitin-dependent Protein Catabolic Process Proteolysis Polyubiquitin Modification-dependent Protein Binding	Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Positive Regulation Of Phosphate Metabolic Process Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT