NOA1 and NFU1

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		NOA1	NFU1
Name		nitric oxide associated 1	NFU1 iron-sulfur cluster scaffold
Structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Matrix Side Of Mitochondrial Inner Membrane	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding GTP Binding	Iron Ion Binding Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Apoptotic Process Mitochondrion Organization Mitochondrial Ribosome Assembly	Iron-sulfur Cluster Assembly Protein Maturation
Pathways		None	Protein lipoylation
GWAS		Automobile speeding propensity ( 30643258 ) Coronary artery disease ( 26343387 29212778 ) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975 ) Height ( 28552196 ) Mean spheric corpuscular volume ( 32888494 ) Platelet count ( 29403010 )	No GWAS studies recorded
Interacting Genes		15 interacting genes: ABCB8 ABCF3 AIFM1 ARF1 BOK CCL14 COL9A2 DCTPP1 GRB10 H1-0 HSPA8 MPP3 NFU1 RBM22 WDR18	23 interacting genes: AGTRAP APOC1 APOC2 APOC4 CALCOCO2 CIDEB CMTM5 COIL DESI2 EPM2A FKBP7 HIRA HSPB1 MDK MORN3 NOA1 RHBDD2 SDCBP2 SH3BP4 TFIP11 TRIM23 ZNF688 ZSCAN5A
Entrez ID		84273	27247
HPRD ID		12823	12163
Ensembl ID		ENSG00000084092	ENSG00000169599
Uniprot IDs		Q8NC60	Q9UMS0
PDB IDs		8CSP	2LTM 2M5O
GO Terms Enriched among Interactors		Prp19 Complex	High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Acylglycerol Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Positive Regulation Of Autophagy Very-low-density Lipoprotein Particle Assembly Regulation Of Autophagy Chylomicron Phospholipid Efflux Negative Regulation Of Lipoprotein Particle Clearance Identical Protein Binding Negative Regulation Of Cholesterol Transport Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Plasma Lipoprotein Particle Clearance Lipid Transport Cholesterol Efflux Positive Regulation Of Catabolic Process Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Metabolic Process Lipid Storage Regulation Of Phospholipid Metabolic Process Plasma Lipoprotein Particle Remodeling Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Negative Regulation Of Phosphatidylcholine Catabolic Process Negative Regulation Of Protein Kinase C Signaling Defecation HIR Complex Negative Regulation Of Hydrolase Activity Carbohydrate Phosphatase Activity Lipid Homeostasis Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Spliceosomal Complex Disassembly