NOA1 and COL9A2

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		NOA1	COL9A2
Name		nitric oxide associated 1	collagen type IX alpha 2 chain
Structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Matrix Side Of Mitochondrial Inner Membrane	Extracellular Region Collagen Trimer Collagen Type IX Trimer Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding GTP Binding	Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Protein Homodimerization Activity
	Biological Process	Apoptotic Process Mitochondrion Organization Mitochondrial Ribosome Assembly	Skeletal System Development
Pathways		None	Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization
Diseases		None	Multiple epiphyseal dysplasia (MED)
GWAS		Automobile speeding propensity ( 30643258 ) Coronary artery disease ( 26343387 29212778 ) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975 ) Height ( 28552196 ) Mean spheric corpuscular volume ( 32888494 ) Platelet count ( 29403010 )	Appendicular lean mass ( 33097823 ) Hip circumference adjusted for BMI ( 34021172 )
Interacting Genes		15 interacting genes: ABCB8 ABCF3 AIFM1 ARF1 BOK CCL14 COL9A2 DCTPP1 GRB10 H1-0 HSPA8 MPP3 NFU1 RBM22 WDR18	10 interacting genes: COL2A1 ERBB2 FEZ1 HAP1 MAG MEOX2 MTNR1A NOA1 UBQLN1 UBQLN2
Entrez ID		84273	1298
HPRD ID		12823	00373
Ensembl ID		ENSG00000084092	ENSG00000049089
Uniprot IDs		Q8NC60	Q14055
PDB IDs		8CSP	5CTD 5CTI 5CVA 5CVB
GO Terms Enriched among Interactors		Prp19 Complex	Regulation Of Organelle Transport Along Microtubule Autophagosome Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Cellular Response To Growth Factor Stimulus Regulation Of Microtubule-based Process Myelin Sheath Regulation Of Microtubule-based Movement Autophagy Positive Regulation Of Neurotrophin Production Regulation Of Organelle Assembly Mitochondrion Localization Regulation Of Autophagosome Assembly Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Regulation Of Vacuole Organization Regulation Of Macroautophagy Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Store-operated Calcium Channel Activity Response To Growth Factor Roof Of Mouth Development Signaling Receptor Binding ERBB3:ERBB2 Complex Cytoplasmic Vesicle Myelination Axon Ensheathment Mesaxon Regulation Of Transmembrane Transporter Activity Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Autophagy Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Collagen Type II Trimer RNA Polymerase I Core Binding Ganglioside GT1b Binding Brain-derived Neurotrophic Factor Binding Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Autophagosome Organization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway System Development Positive Regulation Of Proteasomal Protein Catabolic Process Collagen Type XI Trimer Anterior Head Development Negative Regulation Of Immature T Cell Proliferation In Thymus Neuron Projection Development ErbB-3 Class Receptor Binding Regulation Of Cellular Localization