STX7 and SNAP29

Number of citations: 0 (PubMedID 11423532)
Data Source: HPRD (in vitro)

		STX7	SNAP29
Name		syntaxin 7	synaptosome associated protein 29
Structure		No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Tertiary Granule Secretory Vesicle	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Golgi Apparatus Centrosome Cytosol Plasma Membrane Cilium Membrane Ciliary Pocket Membrane SNARE Complex Cytoplasmic Vesicle Azurophil Granule Membrane Cell Projection Ciliary Membrane Presynapse
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle-mediated Transport Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane	Exocytosis Vesicle Targeting Autophagy Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Cell Projection Organization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cilium Assembly Membrane Fusion Autophagosome Maturation
Pathways		None	Neutrophil degranulation Intra-Golgi traffic
Diseases		None	Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome
GWAS		A body shape index ( 34021172 ) Cutaneous leishmaniasis ( 32830257 ) High light scatter reticulocyte count ( 27863252 32888494 ) High light scatter reticulocyte percentage of red cells ( 27863252 32888494 ) Immature fraction of reticulocytes ( 32888494 ) Mean spheric corpuscular volume ( 32888494 ) Red cell distribution width ( 32888494 27863252 ) Reticulocyte count ( 27863252 32888494 ) Reticulocyte fraction of red cells ( 27863252 32888494 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )	No GWAS studies recorded
Interacting Genes		52 interacting genes: ANKS6 AQP6 ARL13B CERS4 CISD2 CREB3 CREB3L1 CYBRD1 EBP ELOVL5 ENTPD2 FAM174A FAM210B FKBP7 GJC3 HSD17B11 HSD17B13 JAGN1 LIME1 LMNA MAPK6 MFF MGST3 MRM1 MTUS1 NAPA REEP1 RETREG3 RIC3 SAR1A SLC10A1 SLC10A6 SLC18A1 SLC35D4 SNAP29 STX1A STX2 STX6 STX8 TM4SF19 TMEM205 TMEM267 TMEM80 TMPRSS2 TMX2 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B ZFYVE27	24 interacting genes: AP2A1 ATF4 CD7 DNAJC5 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 NAPB NTAQ1 RASSF7 STX12 STX17 STX1A STX1B STX2 STX3 STX6 STX7 TXNRD3 VAMP1 VAMP7
Entrez ID		8417	9342
HPRD ID		04449	11968
Ensembl ID		ENSG00000079950	ENSG00000099940
Uniprot IDs		O15400	O95721
PDB IDs		Not available	4WY4 7BV6
GO Terms Enriched among Interactors		Organelle Membrane Fusion Vesicle Fusion Membrane Fusion SNAP Receptor Activity Organelle Fusion SNARE Complex Organelle Localization By Membrane Tethering Membrane Membrane Docking Vesicle Organization Syntaxin Binding Vesicle Docking Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNARE Binding Chloride Channel Inhibitor Activity Membrane Organization Establishment Of Protein Localization Protein Transport Autophagosome Maturation Intracellular Protein Transport CORVET Complex Organelle Localization Vesicle-mediated Transport Endomembrane System Lysosomal Membrane Intracellular Protein Localization Autophagy Protein Binding Protein-containing Complex Disassembly Vesicle Docking Involved In Exocytosis Establishment Of Localization In Cell Late Endosome Membrane HOPS Complex Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Organelle Organization Endosome To Lysosome Transport Steroid Dehydrogenase Activity Cellular Localization Endoplasmic Reticulum Tubular Network Organization Exocytosis Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Cytoplasmic Vesicle Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Positive Regulation Of Histamine Secretion By Mast Cell Vesicle Tethering Complex Recycling Endosome Presynaptic Active Zone Membrane	SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion SNARE Binding Organelle Fusion Membrane Fusion Vesicle Docking Vesicle-mediated Transport Organelle Localization By Membrane Tethering Membrane Docking Vesicle Organization Intracellular Protein Transport Endomembrane System Intracellular Transport Establishment Of Localization In Cell Protein Transport Cellular Localization Establishment Of Protein Localization Vesicle-mediated Transport In Synapse Membrane Organization Exocytosis Intracellular Protein Localization Organelle Localization Regulation Of Synaptic Vesicle Priming Syntaxin Binding Secretion By Cell Synaptic Vesicle Organelle Organization Synaptic Vesicle Membrane Endocytic Recycling Secretion Ciliary Pocket Membrane Presynaptic Active Zone Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Recycling Endosome Membrane Regulated Exocytosis Synaptic Vesicle Exocytosis Calcium-ion Regulated Exocytosis Synaptic Vesicle Endocytosis Endosomal Transport Presynaptic Endocytosis Vesicle-mediated Transport To The Plasma Membrane Golgi Vesicle Transport ATP-dependent Protein Binding Chloride Channel Inhibitor Activity Plasma Membrane Azurophil Granule Membrane Regulation Of Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane