KBTBD7 and BLMH

Number of citations: 0 (PubMedID 16189514)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		KBTBD7	BLMH
Name		kelch repeat and BTB domain containing 7	bleomycin hydrolase
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cul3-RING Ubiquitin Ligase Complex	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Aminopeptidase Activity Carboxypeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Identical Protein Binding Cysteine-type Aminopeptidase Activity
	Biological Process	Negative Regulation Of Signal Transduction Protein Ubiquitination Regulation Of Rac Protein Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination	Protein Polyubiquitination Proteolysis Response To Xenobiotic Stimulus Response To Toxic Substance Homocysteine Catabolic Process
Pathways		Regulation of RAS by GAPs Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Antigen processing: Ubiquitination & Proteasome degradation
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		20 interacting genes: BARD1 BLMH C8orf33 CCDC106 CPT1A DRD2 DUSP23 GABARAP GABARAPL1 GABARAPL2 HAP1 KLF15 LRIF1 MAP1LC3B MAP1LC3C MEOX2 NFKBIE PHC2 PSME3 VANGL2	20 interacting genes: AP1M2 APP CDC42 CEBPA CYP2C8 ECSIT KBTBD7 MAST1 NTAQ1 NXF1 PDPK1 PGLS RNF32 RPL11 RPL29 TNPO2 TNPO3 TRIM47 TRIO UBE2I
Entrez ID		84078	642
HPRD ID		13759	03870
Ensembl ID		ENSG00000120696	ENSG00000108578
Uniprot IDs		Q8WVZ9	Q13867
PDB IDs		Not available	1CB5 2CB5 7V5L 7V5S 7V5T 7XF9
GO Terms Enriched among Interactors		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagy Autophagosome Assembly Autophagosome Organization Phospholipid Binding Protein-containing Complex Disassembly GABA Receptor Binding Macroautophagy Vacuole Organization Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Organelle Assembly Response To Nutrient Levels Beta-tubulin Binding Ubiquitin Protein Ligase Binding Catabolic Process Cytoplasmic Vesicle Microtubule Regulation Of Synaptic Transmission, GABAergic Regulation Of Protein Catabolic Process Negative Regulation Of MRNA 3'-end Processing Positive Regulation Of Neurotrophin Production Response To Stress Organelle Membrane Long-chain Fatty Acid Transport	Cytosol Cytoplasm Postsynapse Intracellular Transport Nuclear Transport Nucleocytoplasmic Transport Nuclear Import Signal Receptor Activity